[HTML][HTML] Leptomeningeal carcinomatosis: a call for optimizing diagnostic sensitivity by the hematology laboratory

B Lardinois, L Miller, A Randazzo, T Laurent… - Case reports in …, 2021 - karger.com
… In the cerebrospinal fluid (CSF), the demonstration of malignant cells by cytological examination
is currently the gold standard for the diagnosis of leptomeningeal carcinomatosis (LC). …

EpCAM-based flow cytometry in cerebrospinal fluid greatly improves diagnostic accuracy of leptomeningeal metastases from epithelial tumors

B Milojkovic Kerklaan, D Pluim, M Bol, I Hofland… - Neuro …, 2016 - academic.oup.com
… Moderate diagnostic accuracy of MRI and initial cerebrospinal fluid (CSF) cytology analysis
results in at least 10%–15% false negative diagnoses of leptomeningeal metastases (LM) of …

Novel methods to diagnose leptomeningeal metastases in breast cancer

L Angus, JWM Martens, MJ van den Bent… - Neuro …, 2019 - academic.oup.com
… of the brain and/or spinal cord and cytological examination of cerebrospinal fluid (CSF). Both
… in close contact with cerebrospinal fluid (CSF). Once shed into the CSF, cancer cells may …

Immunohistochemical analysis of the cerebrospinal fluid for carcinomatous and lymphomatous leptomeningitis

A Hovestadt, SC Henzen-Logmans… - British journal of cancer, 1990 - nature.com
analysis in relation to the standard cytological examination of the cerebrospinal fluid (CSF)
in … or a haematological malignancy and possible leptomeningeal disease, 68 CSF-samples …

Leptomeningeal metastasis of primary central nervous system (CNS) neoplasms

HH Engelhard, LA Corsten - Leptomeningeal metastases, 2005 - Springer
… lymphoma, seeding of the cerebrospinal fluid space is a critical … evidence of leptomeningeal
metastases without clear impact … in standard protocols for CSF analysis, staging of the entire …

Early Detection of Leptomeningeal Metastasis by PCR Examination of Tumor-derived K-ras DNA in Cerebrospinal Fluid

DW Swinkels, JB de Kok, A Hanselaar… - Clinical …, 2000 - academic.oup.com
… melanoma are the most common to metastasize to the leptomeninges (1). The prognosis
for … of LMM requires cytological detection of malignant cells in the cerebrospinal fluid (CSF). …

The utility of repeated cytologic evaluation of cerebrospinal fluid in individuals with metastatic breast cancer

JB Patel, J Xing, D Deeds, GT Budd, CN Booth… - … Society of Cytopathology, 2016 - Elsevier
… postulated to spread via the cerebrospinal fluid (CSF). Cytologic evaluation of the CSF is …
with signs and symptoms that suggest leptomeningeal carcinomatosis (LMC) rather than an …

Comparative spine imaging in leptomeningeal metastases

MC Chamberlain - Journal of neuro-oncology, 1995 - Springer
… All patients had LM as defined by either positive CSF cytology or a clinical syndrome and …
CSF cytology notwithstanding multiple CSF examination from at least 2 cerebrospinal fluid (…

Cerebrospinal fluid cytology in patients with cancer: minimizing false‐negative results

MJ Glantz, BF Cole, LK Glantz, J Cobb… - … Journal of the …, 1998 - Wiley Online Library
… Detection of malignant cells on cytologic examination of the cerebrospinal fluid (CSF) is
the diagnostic gold standard for leptomeningeal carcinomatosis. The absence of cells is a …

Diagnostic significance of cerebrospinal fluid EGFR mutation analysis for leptomeningeal metastasis in non-small-cell lung cancer patients harboring an active EGFR …

S Sasaki, Y Yoshioka, R Ko, Y Katsura, Y Namba… - Respiratory …, 2016 - Elsevier
metastases together with leptomeningeal metastasis (LM). We performed cerebrospinal fluid
analysis focusing on cytology … Despite negative cytology results, we detected the X19del …