Leukocyte analysis and differentiation using high speed microfluidic single cell impedance cytometry

D Holmes, D Pettigrew, CH Reccius, JD Gwyer… - Lab on a Chip, 2009 - pubs.rsc.org
… and simple full blood cell analysis systems that could be used … cell impedance cytometer
that performs a white blood cell … that measure the impedance of single cells at two frequencies. …

Microfluidic lysis of human blood for leukocyte analysis using single cell impedance cytometry

X Han, C van Berkel, J Gwyer, L Capretto… - Analytical …, 2012 - ACS Publications
… full blood count using impedance analysis. A microfluidic network design for red blood cell
(RBC) lysis is presented, and the diffusive mixing processes are analyzed using experimental …

Label-free differential leukocyte counts using a microfabricated, single-cell impedance spectrometer

D Holmes, T Sun, H Morgan, J Holloway… - SENSORS, 2007 …, 2007 - ieeexplore.ieee.org
… the theory for impedance analysis of a single cell in a microchip. We … on impedance alone,
the three main leukocyte (white blood cell) sub… Fluorescence analysis of the cells is performed …

Label-free leukocyte sorting and impedance-based profiling for diabetes testing

C Petchakup, HM Tay, WH Yeap, R Dalan… - Biosensors and …, 2018 - Elsevier
… sorter prior to single-cell impedance measurement in a microfluidic … detected between healthy
and activated leukocytes (TNF-α/… leukocyte phenotypes and suggest leukocyte impedance

Label-free whole blood cell differentiation based on multiple frequency AC impedance and light scattering analysis in a micro flow cytometer

P Simon, M Frankowski, N Bock, J Neukammer - Lab on a Chip, 2016 - pubs.rsc.org
… AC impedance cytometer for blood cell differentiation. The estimated limit of detection (LOD)
for particle volumes using threshold based analyses is … of impedance signals of leukocyte

Microfluidic impedance cytometry for blood cell analysis

H Morgan, D Spencer - 2014 - books.rsc.org
… is approximately 1000 to 1, therefore to enable measurement of the leukocytes in a practical
time scale, the red cells must be removed so that they are not counted. If the RBCs were …

Microfluidic impedance cytometry of tumour cells in blood

D Spencer, V Hollis, H Morgan - Biomicrofluidics, 2014 - pubs.aip.org
… have a large membrane capacitance and size, enabling clear discrimination from all other
leukocytes. Impedance analysis is used to follow changes in cell viability when cells are kept …

Inherent bioelectrical parameters of hundreds of thousands of single leukocytes based on impedance flow cytometry

H Tan, M Wang, Y Zhang, X Huang, D Chen… - Cytometry Part …, 2022 - Wiley Online Library
… of white blood cells based on a home-developed impedance flow cytometry with corresponding
3-part differential of leukocytes realized. More specifically, leukocytes were separated …

Integrated inertial-impedance cytometry for rapid label-free leukocyte isolation and profiling of neutrophil extracellular traps (NETs)

C Petchakup, HM Tay, KHH Li, HW Hou - Lab on a Chip, 2019 - pubs.rsc.org
… co-flow with leukocytes through the … impedance readout and complicating signal analysis.
Hence, there exists a critical need to develop impedance biosensing platforms with leukocyte

Comparison of venous and capillary differential leukocyte counts using a standard hematology analyzer and a novel microfluidic impedance cytometer

VS Hollis, JA Holloway, S Harris, D Spencer… - 2012 - journals.plos.org
… The cytometer is based on electrical impedance measurements of single cells flowing …
impedance cytometer (MIC) [11]–[13]. In this study the MIC is used to enumerate leukocyte counts …