… and other leukocytes in concert with P- and E-selectins on endothelial cells interact with
endothelial and leukocyte carbohydrate ligands respectively, to assist leukocyte binding to …

… endothelial adhesive platforms in associated with tetraspanin CD151. Hepatocytes can
mediate leukocyte … L-SIGN blockade reduces colon cancer metastasis in murine models. LSEC, …

… metastases or indirectly, for example, by induction of thrombosis. In this review, we discuss
how endothelial function is affected in individuals with cancer … and recruitment of leukocytes. …

… of cancer's metastatic process is essential in the treatment of this difficult disease [1]. It is
well-known that human pancreatic cancers … ) and often develop liver metastases. Invasive and …

… interstitial fluid and migrating leukocytes and tumor cells. The lymphatic endothelial cell (LEC) …
of LN and distant metastasis, observed in several types of human cancers, including lung …

… In conclusion, we have shown for the first time that inflamed lymphatic endothelium promotes
the exit of leukocytes from tissue to afferent lymph through newly induced expression of the …

… for cancer cells than the overlying endothelium [14], our laboratory initially postulated that
endothelial injury … proteases as they appear to be in the case of leukocytes [32, 33]. It is equally …

… treatment did not induce metastasis formation by tumor lines that were not metastatic, nor
changed their metastatic … cell that extravasates during metastasis is a leukocyte that leaves the …

… leukocytes, platelets, and endothelial cells, which are likely to mediate the initial steps of
hematogenous metastasis. … In conclusion, leukocytes may facilitate metastasis by potentiating …

… the adhesion and rolling of leukocytes to and on the endothelium [18]. Then, the rolling
leukocytes sense chemokines on the surface of the endothelium, which activates their integrins …