… The effect of dietary restriction (DR) on life span in different organisms. Life span is
increased in a wide range of species, although the protocol used to apply DR varies greatly for …

… dietary restriction (DR). DR in this broad sense includes caloric restriction (CR), in which total
calorie intake is reduced, as well as dietary interventions involving the restriction of specific …

… restriction (CR) to refer to a dietary intervention with an overall 20–40% reduction of total
caloric intake, and dietary restriction to represent a broader scope of dietary … pattern restrictions. …

… this, because at more moderate levels of dietary restriction, chico1 extends life-span. …
extension of life-span by chico1 at the level of dietary restriction that maximizes life-span. This might …

… Evolutionarily conserved molecular mechanisms for dietary restriction result in inhibition of
… life span in yeast, worms, flies, and mice. In worms and flies, rapamycin-mediated life span …

… fed), 948 (diet-restricted). dietary restriction in any phase of the postweaning lifespan and
that the magnitude of … Life span study of SPF Fischer 344 male rats fed ad libitum or restricted …

… Unfortunately, dietary management and exercise frequently fail as remedies, underscoring
… metabolic disorders and enhance life span and health span. Using calorie restriction (CR)—…

… Prolongation of life due to dietary restriction and associated with stunting was apparently
first observed in rats (69). While less than one-third of the full-fed controls lived longer than 24 …

… and extending healthspan and lifespan in diverse species, … of dietary restriction in these
mammalian model organisms and discuss accumulating data that suggest that dietary restriction …

… Objective—To evaluate the effects of 25% diet restriction on life span of dogs and on …
Objective—To evaluate the effects of 25% diet restriction on life span of dogs and on markers of …