Myeloid lineage progenitors give rise to vascular endothelium

AS Bailey, H Willenbring, S Jiang… - Proceedings of the …, 2006 - National Acad Sciences
vascular endothelial cells can differentiate from common myeloid progenitors and
granulocyte/macrophage progenitors. … Our results demonstrate that vascular endothelial cells can …

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

A Ditadi, CM Sturgeon, J Tober, G Awong… - Nature cell …, 2015 - nature.com
… specified towards a vascular endothelial fate, generating a progenitor population that can be
directed to an arterial (CD73 … These endothelial cells derived from the vascular endothelial

Resident vascular endothelial progenitor definition and function: the age of reckoning

J Dight, J Zhao, C Styke, K Khosrotehrani, J Patel - Angiogenesis, 2022 - Springer
… Hematopoietic angiogenic cells exhibited characteristics of myeloid origins and function
whereas OECs demonstrated commitment to the endothelial lineage as had been previously …

[HTML][HTML] The developmental origins and lineage contributions of endocardial endothelium

A Nakano, H Nakano, KA Smith, NJ Palpant - Biochimica et Biophysica …, 2016 - Elsevier
vascular endothelial growth factor receptor Flk1 (Kdr) were shown to be capable of generating
cardiomyocytes and endothelial cells (as well as vascularcardiovascular progenitor cell …

Is endothelium the origin of endothelial progenitor cells?

MC Yoder - Arteriosclerosis, thrombosis, and vascular biology, 2010 - Am Heart Assoc
endothelial cells that display properties consistent with those of a progenitor cell for the
endothelial lineage. … Vascular endothelial cells also regulate arterial reactivity to various stresses …

[HTML][HTML] Diverse cellular origins of adult blood vascular endothelial cells

JB Aquino, R Sierra, LA Montaldo - Developmental Biology, 2021 - Elsevier
… on local resident ECs or endothelial progenitor cells (EPCs). … plasticity were shown to
originate endothelial-like cells (ELCs… of cells committed to specific lineages to change their fate …

The heart endocardium is derived from vascular endothelial progenitors

M Milgrom-Hoffman, Z Harrelson, N Ferrara… - …, 2011 - journals.biologists.com
… ; we suggest that the rest of the endocardium in these regions derives from the Isl1 – endothelial
lineage. Finally, genetic ablation of Flk1 in mouse in the Mesp1 and Tie2 (Tek – Mouse …

Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells

K Ohtani, GJ Vlachojannis, M Koyanagi… - Circulation …, 2011 - Am Heart Assoc
endothelial and hematopoietic progenitor cells can undergo differentiation toward the
endothelial lineage … The basal mechanisms for endothelial specification and endothelium-specific …

Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration, and vasculogenesis

NM Caplice, B Doyle - Stem cells and development, 2005 - liebertpub.com
… the current understanding of the lineage of these cells, that … oxide in response to vascular
endothelial growth factor (VEGF) … an adult vascular progenitor cell with dual endothelial and …

Resident vascular progenitor cells—diverse origins, phenotype, and function

PJ Psaltis, A Harbuzariu, S Delacroix… - … of cardiovascular …, 2011 - Springer
… (BMP) families, vascular endothelial growth factor (VEGF) … VEGFR2 + progenitors possess
pro-angiogenic, endothelial … true EPCs but rather progenitors of hematopoietic lineage [57, 58]…