Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing
… linked-read WGS on 23 mCRPC biopsy specimens and analyzed cell-free DNA sequencing
… In addition to frequent rearrangements affecting known prostate cancer genes, we observed …
… In addition to frequent rearrangements affecting known prostate cancer genes, we observed …
Identifying phased mutations and complex rearrangements in human prostate cancer cell lines through linked-read whole-genome sequencing
… prostate cancer research, but their genomes remain incompletely characterized. Here, we
utilized whole-genome linked-read sequencing for … lines in prostate cancer research including …
utilized whole-genome linked-read sequencing for … lines in prostate cancer research including …
Allelic phasing of genomic alterations through linked read whole genome sequencing in human prostate cancer cell lines
MT Pham, H Gupta, A Gupta, A Vaghasia, AM Skaist… - Cancer Research, 2021 - AACR
… sequencing with allelic phasing of genomic alterations has not been … whole genome
linked-read sequencing of high molecular weight DNA (>60Kbp) from eight common prostate cancer …
linked-read sequencing of high molecular weight DNA (>60Kbp) from eight common prostate cancer …
Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing
… reads (range, 1.1 (CSPC4) to 5.2 (CRPC5) million reads) for the plasma samples from patients
with prostate cancer … and men with prostate cancer we first calculated the genome-wide z-…
with prostate cancer … and men with prostate cancer we first calculated the genome-wide z-…
Whole-genome sequence of the metastatic PC3 and LNCaP human prostate cancer cell lines
… prostate cancer cell lines are widely studied, having been described in thousands of
publications over the last four decades. Here, we report short-read whole-genome sequencing (…
publications over the last four decades. Here, we report short-read whole-genome sequencing (…
Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole Genome Sequencing
MT Pham, H Gupta, A Gupta, A Vaghasia, A Skaist… - bioRxiv, 2021 - biorxiv.org
… Linked-read sequencing of human PCa cell lines We performed linked read sequencing of
high molecular weight DNA from … prostatic epithelial cell line RWPE-1 (Fig. 1A; Table S1). The …
high molecular weight DNA from … prostatic epithelial cell line RWPE-1 (Fig. 1A; Table S1). The …
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer
SG Zhao, M Bootsma, S Zhou, R Shrestha… - Nature Genetics, 2024 - nature.com
… the effects of regulatory regions linked through 3D DNA structure to the promoters of genes,
we integrated our Hi-C data with linear prostate cancer histone modification ChIP–seq data …
we integrated our Hi-C data with linear prostate cancer histone modification ChIP–seq data …
Exploring the tumor genomic landscape of aggressive prostate cancer by whole‐genome sequencing of tissue or liquid biopsies
S Weiss, P Lamy, M Rusan, M Nørgaard… - … Journal of Cancer, 2024 - Wiley Online Library
… age-related signatures SBS1 and SBS5. In addition, they detected the DNA repair-related …
, supporting our finding that DNA repair-related signatures were more frequently observed in …
, supporting our finding that DNA repair-related signatures were more frequently observed in …
Prostate cancer genomics by high-throughput technologies: genome-wide association study and sequencing analysis
H Nakagawa - Endocrine-related cancer, 2013 - erc.bioscientifica.com
… in high-throughput genomic technologies enable us to analyze prostate cancer genomics
more … Next-generation sequencing (NGS) can analyze whole genomes (3 Gb) and the whole …
more … Next-generation sequencing (NGS) can analyze whole genomes (3 Gb) and the whole …
Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer
C Wu, AW Wyatt, AV Lapuk, A McPherson… - The Journal of …, 2012 - Wiley Online Library
… a novel and highly aggressive case of prostate cancer with unique biological features and, …
of genome, exome and transcriptome sequences for basic tumour biology, sequence‐based …
of genome, exome and transcriptome sequences for basic tumour biology, sequence‐based …
相关搜索
- whole genome sequencing prostate cancer
- structural alterations linked read genome sequencing
- plasma genome sequencing prostate cancer therapy
- transcriptome sequencing prostate cancer
- genomic landscape prostate cancer
- human prostate cancer cell lines
- genomic profiling of prostate cancer
- prostate cancer genomics wide association studies
- longitudinal genomic analysis prostate cancer
- historic perspective genomics of prostate cancer
- molecular genetics of prostate cancer
- metastatic prostate cancer genomic hallmarks
- intratumor heterogeneity prostate cancer
- clonal evolution prostate cancer
- prostate cancer genomics high throughput technologies
- prostate cancer genomics risk assessment