… linked-read WGS on 23 mCRPC biopsy specimens and analyzed cell-free DNA sequencing
… In addition to frequent rearrangements affecting known prostate cancer genes, we observed …

… prostate cancer research, but their genomes remain incompletely characterized. Here, we
utilized whole-genome linked-read sequencing for … lines in prostate cancer research including …

… sequencing with allelic phasing of genomic alterations has not been … whole genome
linked-read sequencing of high molecular weight DNA (>60Kbp) from eight common prostate cancer …

… reads (range, 1.1 (CSPC4) to 5.2 (CRPC5) million reads) for the plasma samples from patients
with prostate cancer … and men with prostate cancer we first calculated the genome-wide z-…

… prostate cancer cell lines are widely studied, having been described in thousands of
publications over the last four decades. Here, we report short-read whole-genome sequencing (…

… Linked-read sequencing of human PCa cell lines We performed linked read sequencing of
high molecular weight DNA from … prostatic epithelial cell line RWPE-1 (Fig. 1A; Table S1). The …

… the effects of regulatory regions linked through 3D DNA structure to the promoters of genes,
we integrated our Hi-C data with linear prostate cancer histone modification ChIP–seq data …

… age-related signatures SBS1 and SBS5. In addition, they detected the DNA repair-related …
, supporting our finding that DNA repair-related signatures were more frequently observed in …

… in high-throughput genomic technologies enable us to analyze prostate cancer genomics
more … Next-generation sequencing (NGS) can analyze whole genomes (3 Gb) and the whole …

… a novel and highly aggressive case of prostate cancer with unique biological features and, …
of genome, exome and transcriptome sequences for basic tumour biology, sequence‐based …