Ion pair transport across membranes
R Neubert - Pharmaceutical research, 1989 - Springer
… discusses drugs and counter ions suitable for ion pair transport (IPT). Ion pairing is shown
to … The transport of ion pairs across lipid membranes (ion pair transport) appears to follow a …
to … The transport of ion pairs across lipid membranes (ion pair transport) appears to follow a …
Ion Pairing of Cationic and Anionic Ir(III) Photosensitizers for Photocatalytic CO2 Reduction at Lipid–Membrane Surfaces
S Takizawa, T Okuyama, S Yamazaki… - Journal of the …, 2023 - ACS Publications
… Herein, we report the synthesis of [Ir1 + ][Ir2 – ] as a new ion pair and … -3-phosphocholine
(DPPC) vesicle membranes, by comparing the … effect of ion pairing at the vesicle membrane. …
(DPPC) vesicle membranes, by comparing the … effect of ion pairing at the vesicle membrane. …
Free Energy for the Permeation of Na+ and Cl− Ions and Their Ion-Pair through a Zwitterionic Dimyristoyl Phosphatidylcholine Lipid Bilayer by Umbrella Integration …
… kcal/mol near its center, ion-pairing between such hydrophilic ions as Na + and Cl − does …
that ion-pairing between ions of opposite charge and solvent philicity could enhance ion …
that ion-pairing between ions of opposite charge and solvent philicity could enhance ion …
Recent progress in hydrophobic ion-pairing and lipid-based drug delivery systems for enhanced oral delivery of biopharmaceuticals
G Noh, T Keum, S Bashyal, JE Seo, L Shrawani… - Journal of …, 2022 - Springer
… However, only lipophilic substances can be stably incorporated in LDDSs, and
hydrophilic peptides and proteins require lipidation via, eg, hydrophobic ion pairing (HIP). …
hydrophilic peptides and proteins require lipidation via, eg, hydrophobic ion pairing (HIP). …
Applications of the ion-pair concept to hydrophilic substances with special emphasis on peptides
D Quintanar-Guerrero, E Allémann, H Fessi… - Pharmaceutical …, 1997 - Springer
… parameters involved in ion pair formation with special … of drugs, and on the enhanced
absorption as ion-pairs. Results from … that ionic drug transport across an artificial lipid membrane …
absorption as ion-pairs. Results from … that ionic drug transport across an artificial lipid membrane …
[HTML][HTML] Counterion-mediated membrane penetration: cationic cell-penetrating peptides overcome Born energy barrier by ion-pairing with phospholipids
… to explore if solvation by ion-pairing to hydrophobic counter-ions may serve as a mechanism
for cell internalisation. We demonstrate that anionic lipids can aid peptide partitioning into …
for cell internalisation. We demonstrate that anionic lipids can aid peptide partitioning into …
The dermal delivery of lignocaine: influence of ion pairing
C Valenta, U Siman, M Kratzel, J Hadgraft - International journal of …, 2000 - Elsevier
… The purpose of the present study was to determine the significance of ion pairing on the
permeation of lignocaine. Results of diffusion studies through polydimethylsiloxane (PDMS) at …
permeation of lignocaine. Results of diffusion studies through polydimethylsiloxane (PDMS) at …
Ion pair-mediated transport of metoprolol across a three lipid-component PAMPA system
… Potential ion pair-mediated transport of metoprolol was challenged via a self-… ion pairing
as a mechanism to enhance metoprolol transport across A-PAMPA and assumed that ion pair-…
as a mechanism to enhance metoprolol transport across A-PAMPA and assumed that ion pair-…
[HTML][HTML] Distribution of ion pairs into a bilayer lipid membrane and its effect on the ionic permeability
T Omatsu, K Hori, N Ishida, K Maeda… - Biochimica et Biophysica …, 2021 - Elsevier
… validate the ion-pair distribution model for ionic membrane transport through a BLM based
on the distribution cation and anion by evaluating the distribution constant of ions between an …
on the distribution cation and anion by evaluating the distribution constant of ions between an …
Hydrophobic ion pairing of a GLP-1 analogue for incorporating into lipid nanocarriers designed for oral delivery
R Ismail, TNQ Phan, F Laffleur, I Csóka… - European journal of …, 2020 - Elsevier
… The lipophilic character of peptides can be tremendously improved by hydrophobic ion
pairing (HIP) with counterions to be efficiently incorporated into lipid-based nanocarriers (NCs). …
pairing (HIP) with counterions to be efficiently incorporated into lipid-based nanocarriers (NCs). …
相关搜索
- anionic lipid membranes ion parameters
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- hydrophobic ion pairing
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- ion pair concept
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- ion pairing lipid nanocarriers
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