The role of glucose and lipid metabolism in growth and survival of cancer cells

C Brault, A Schulze - Metabolism in Cancer, 2016 - Springer
… address the requirement of PKM2 for cancer development using a genetic model revealed
differential metabolic requirements of quiescent and proliferating cancer cells (Israelsen et al. …

Lipid metabolism dynamics in cancer stem cells: potential targets for cancers

J Du, H Qin - Frontiers in Pharmacology, 2024 - frontiersin.org
… between autophagy and lipid metabolism facilitates rapid … lipid metabolism in CSCs and
provide a concise overview of the indispensable role played by LDs, FA, cholesterol metabolism

Lipid metabolism and endocrine resistance in prostate cancer, and new opportunities for therapy

GE Stoykova, IR Schlaepfer - International journal of molecular sciences, 2019 - mdpi.com
… several aspects of PCa lipid metabolism: Synthesis, … lipid metabolism and AR are starting
to emerge, providing new opportunities to re-sensitize tumors to endocrine therapies with lipid

Cancer lipid metabolism confers antiangiogenic drug resistance

H Iwamoto, M Abe, Y Yang, D Cui, T Seki, M Nakamura… - Cell Metabolism, 2018 - cell.com
… is frequently developed in cancer patients, and molecular mechanisms underlying AAD
resistance remain largely unknown. Here we describe AAD-triggered, lipid-dependent metabolic …

The role of lipid metabolism disorders in the development of thyroid cancer

M Lukasiewicz, A Zwara, J Kowalski, A Mika… - International Journal of …, 2024 - mdpi.com
… In this review, we examine lipid metabolism at different stages, … development. Recent
scientific efforts have revealed disturbances in lipid homeostasis that are specific to thyroid cancer, …

Cancer therapy's impact on lipid metabolism: Mechanisms and future avenues

R Bhatnagar, NM Dixit, EH Yang… - Frontiers in …, 2022 - frontiersin.org
… Not surprisingly, cancer-targeting therapies have been linked to metabolic dysregulation
including changes in local and systemic lipid metabolism. Thus, tumor development and cancer

Upregulation of lipid metabolism genes in the breast prior to cancer diagnosis

N Marino, R German, X Rao, E Simpson, S Liu… - … Breast Cancer, 2020 - nature.com
… We further show that the breast tissue susceptible to cancer development has an enrichment
in lipid metabolism-related genes not only in the epithelial compartment but also in the …

The heterogeneity of lipid metabolism in cancer

JK Park, NJ Coffey, A Limoges, A Le - … heterogeneity of cancer metabolism, 2018 - Springer
… are now in various stages of clinical development, and one approach worth highlighting is …
on the significance of heterogeneity in cancer lipid metabolism as we translate basic science …

A pan-cancer analysis of lipid metabolic alterations in primary and metastatic cancers

G Liu, Y Yang, X Kang, H Xu, J Ai, M Cao, G Liu - Scientific Reports, 2023 - nature.com
… , metastatic tumors analyzed in this study may represent a population whose development
depends on lipid metabolism similarly as normal tissues. Similarly, we also evaluated …

The correlation between lipid metabolism disorders and prostate cancer

J Dłubek, J Rysz, Z Jabłonowski… - Current medicinal …, 2021 - ingentaconnect.com
… in tumor development and progression, including lipid metabolism [63, 64]. Anabolic action
is vital for normal prostate to preserve the secretory function of the prostate gland which are …