Lipid metabolism in cancer progression and therapeutic strategies

Y Fu, T Zou, X Shen, PJ Nelson, J Li, C Wu, J Yang… - MedComm, 2021 - Wiley Online Library
lipid metabolism on the TME in cancer progression. Stromal cells in TME, especially immune
cells, undergo lipid … In addition, lipid metabolites present in the TME play a significant role in …

Emerging roles of lipid metabolism in cancer progression

C Corbet, O Feron - Current Opinion in Clinical Nutrition & …, 2017 - journals.lww.com
… More generally, lipid metabolism has lately gained attention in cancer research as different
… pleiotropic effects in cancer progression. Lipid metabolism and cancer cell adaptation to the …

Alterations of lipid metabolism in cancer: implications in prognosis and treatment

LP Fernández, M Gomez de Cedron… - Frontiers in …, 2020 - frontiersin.org
… In addition, different studies including in vitro, preclinical, and clinical trials have demonstrated
the relevance of lipid metabolism to sustain cancer initiation and progression (6). The …

Lipid metabolism in cancer

CR Santos, A Schulze - The FEBS journal, 2012 - Wiley Online Library
… and the abundance of lipids with signalling functions. Changes in lipid metabolism can affect
… of the alterations in lipid metabolism that have been reported in cancer, at both cellular and …

The role of lipids in cancer progression and metastasis

M Martin-Perez, U Urdiroz-Urricelqui, C Bigas… - Cell metabolism, 2022 - cell.com
lipid catabolism and anabolism for energy and oxidative stress protective purposes. Cancer
cells also harness lipid metabolism to … aiming to reduce lipid availability to cancer cells or to …

Lipid metabolism and cancer progression: The missing target in metastatic cancer treatment

M Omabe, M Ezeani, KN Omabe - journal of applied biomedicine, 2015 - Elsevier
… Here we bring lipid metabolic pathways into focus and summarized details that … lipid
metabolism and indeed adipocyte derived products may important molecular target for better cancer

[HTML][HTML] Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer

J Swierczynski, A Hebanowska… - World journal of …, 2014 - ncbi.nlm.nih.gov
… 519, is elevated in patients with certain types of cancer, its serum level was proposed as
a … in lipid metabolism and other metabolic processes associated with lipid metabolism in …

Lipid metabolism in development and progression of hepatocellular carcinoma

M Sangineto, R Villani, F Cavallone, A Romano… - Cancers, 2020 - mdpi.com
progression of HCC. The aim of this review is to elucidate the mechanisms by which lipid
metabolism … aberrations with new insights in lipidomics and lipid zonation. This will help detect …

New links between lipid accumulation and cancer progression

JT Nickels - Journal of Biological Chemistry, 2018 - ASBMB
… Dysregulation of lipid metabolism is common in cancer cells, but the underlying mechanisms
are poorly understood. Sterol regulatory element–binding proteins (SREBPs) stimulate …

Lipogenesis in cancer progression

C Mounier, L Bouraoui… - … journal of oncology, 2014 - spandidos-publications.com
… General modification of the lipid profile during cancer progression is associated with increased
expression of several genes involved in lipid metabolism (84). Apart from FAS and SCD1, …