Lipid metabolism in cancer
… Mutations in VHL frequently occur in renal cell carcinomas and promote a pseudo-hypoxic
state that leads to the stabilization of HIF1α and HIF2α, even in the presence of oxygen [66]. …
state that leads to the stabilization of HIF1α and HIF2α, even in the presence of oxygen [66]. …
Aberrant lipid metabolism in hepatocellular carcinoma cells as well as immune microenvironment: a review
B Hu, JZ Lin, XB Yang, XT Sang - Cell proliferation, 2020 - Wiley Online Library
… findings of lipid metabolic reprogramming in … lipid metabolism and associated signalling
pathways may suggest a novel strategy to treat HCC by reprogramming cell lipid metabolism or …
pathways may suggest a novel strategy to treat HCC by reprogramming cell lipid metabolism or …
Lipid metabolism in development and progression of hepatocellular carcinoma
… cellular lipidic composition contribute to initiation and progression of HCC. The aim of this
review is to elucidate the mechanisms by which lipid metabolism … lipidomics and lipid zonation. …
review is to elucidate the mechanisms by which lipid metabolism … lipidomics and lipid zonation. …
Lipid metabolism reprogramming in renal cell carcinoma
… In this review, we focus on lipid metabolism dysregulation associated with RCC and ccRCC
… deregulated lipid metabolism in RCC development, including alterations in the metabolism …
… deregulated lipid metabolism in RCC development, including alterations in the metabolism …
Lipid metabolism in cancer: New perspectives and emerging mechanisms
LA Broadfield, AA Pane, A Talebi, JV Swinnen… - Developmental cell, 2021 - cell.com
… molecules to support aberrant cellular replication, dissemination … Lipid metabolism is often
drastically altered in cells undergoing transformation to a malignant phenotype. Tumor cells …
drastically altered in cells undergoing transformation to a malignant phenotype. Tumor cells …
The uniqueness of clear cell renal cell carcinoma: summary of the process and abnormality of glucose metabolism and lipid metabolism in ccRCC
X Qi, Q Li, X Che, Q Wang, G Wu - Frontiers in Oncology, 2021 - frontiersin.org
… of lipid metabolism in ccRCC. Therefore, this review emphasizes the relationship and significance
of lipid metabolism … Effect: Provide a Large Amount of Acetyl-CoA for Lipid Metabolism …
of lipid metabolism … Effect: Provide a Large Amount of Acetyl-CoA for Lipid Metabolism …
Lipid metabolism in cancer cells under metabolic stress
… showed that at least in RCC4 clear cell renal cell carcinoma cells, hypoxic accumulation
of lipid droplets was not mediated by CD36. Further studies are required to study this …
of lipid droplets was not mediated by CD36. Further studies are required to study this …
Targeting lipid metabolism of cancer cells: A promising therapeutic strategy for cancer
Q Liu, Q Luo, A Halim, G Song - Cancer letters, 2017 - Elsevier
… Here, we provide a brief review of the crucial roles of FA metabolism in cancer development…
storage in cancer cells. Understanding the regulation of lipid metabolism in cancer cells has …
storage in cancer cells. Understanding the regulation of lipid metabolism in cancer cells has …
Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma
Z Zhao, J Lu, L Han, X Wang, Q Man, S Liu - Tumor Biology, 2016 - Springer
… lipid metabolism enzymes in clear cell RCC (ccRCC). In the present study, we elucidated the
expression of two lipid metabolism … , which indicated lipid metabolism abnormality might be …
expression of two lipid metabolism … , which indicated lipid metabolism abnormality might be …
Renal lipid metabolism abnormalities in obesity and clear cell renal cell carcinoma
… for clear cell renal cell carcinoma, and is also associated with lipid accumulation in noncancerous
epithelial cells of the proximal tubule, where clear cell renal cell carcinoma originates. …
epithelial cells of the proximal tubule, where clear cell renal cell carcinoma originates. …
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