[HTML][HTML] Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

F Chiappini, A Coilly, H Kadar, P Gual, A Tran… - Scientific reports, 2017 - nature.com
lipid signature of NASH and positioned FADS1 as a significant player in accumulating toxic
lipids … sensitivities to lipids most likely due to differences in the lipid metabolism of such cells …

Individualized Lipid Metabolism-Associated Six-Gene Signature for Prediction of Overall Survival, Immune Infiltration, Immunotherapy Response, and Potential …

S MUHAMMAD, T Fan, L Zhang, S Fei, K Kaur, A Khan… - 2023 - researchsquare.com
… We veri ed that the six-gene lipid metabolism-associated prognostic signature was an
independent prognostic factor for OS in LUSC patients (TCGA cohort) (Figure 8A). We conducted …

[HTML][HTML] Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease

JM Mato, C Alonso, M Noureddin… - World journal of …, 2019 - ncbi.nlm.nih.gov
… Deranged lipid metabolism is also associated with NAFLD progression from steatosis to
NASH, and therefore, alterations in liver and serum lipidomic signatures are good indicators of …

Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma

K Muir, A Hazim, Y He, M Peyressatre, DY Kim, X Song… - Cancer research, 2013 - AACR
… Here we are reporting changes in proteins associated with lipid metabolism. This information
is further integrated with fatty acid profiles carried out in both liver tissue and plasma. …

[HTML][HTML] CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis

X Zhou, F Meng, L Xiao, H Shen - BMC Medical Genomics, 2023 - Springer
… , the association between lipid metabolism and immunotherapy … In addition, reprogramming
lipid metabolism may enhance … predicted by a gene signature related to lipid metabolism [15, …

[HTML][HTML] Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

R Mesnage, M Biserni, S Balu, C Frainay, N Poupin… - Archives of …, 2018 - Springer
… the alterations in gene expression … genes involved in lipid metabolism. This was associated
with an increased oxidative stress reflected by marked disturbances in taurine metabolism. A …

Lipid metabolic-related signature CYP19A1 is a potential biomarker for prognosis and immune cell infiltration in gastric cancer

N Wang, X Huang, Q Long - Journal of inflammation research, 2022 - Taylor & Francis
gene signatures predicting survival of GC. Univariable and multivariable Cox regression
analysis indicated that the lipid metabolism-related genes … a new lipid metabolism-related gene

Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with …

D Mehta, CL Raison, BJ Woolwine, E Haroon… - Brain, behavior, and …, 2013 - Elsevier
… Differential expression of genes related to glucose and lipid metabolism predicts response
… transcriptional signatures reflective of alterations in glucose and lipid metabolism predicted …

[HTML][HTML] A novel lipid prognostic signature of ADCY2, LIPE, and OLR1 in head and neck squamous cell carcinoma

X Gao, N Zhao, L Dong, X Zheng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
… Figure 1 Lipid-related differentially expressed genes (DEGs) in HNSCC. Top 20 of the 65
genes involving lipid metabolism showed abnormal expression in HNSCC from the TCGA …

[HTML][HTML] Whole genome transcript profiling of drug induced steatosis in rats reveals a gene signature predictive of outcome

N Sahini, S Selvaraj, J Borlak - PLoS One, 2014 - journals.plos.org
… In severely affected livers enhanced LD growth paves the way for significant changes in
glucose metabolism, lipid transport and lipid metabolism. To sustain detoxification and demands …