… observed with CNVs overlapping lipid metabolism genes (p-… additional evidence that the
genetic components of risk for … -affecting genes involved in lipid metabolism and expressed …

… This study comprehensively investigated the associations between blood lipid metabolism
… on lipid metabolism. Genetic factors may also contribute to the relationship between blood …

… gallstone formation and clinical implication is to be in a step-by-step manner: genetics,
defects of biliary lipid metabolism… stone formation, and finally clinical symptoms (Fig. 1). Thus, …

… of gallbladder disease with approximately 2000 gene-centric loci involved in lipid metabolism
… ABCC7) or the CYP7A1 gene have been demonstrated to cause gallstones by altering bile …

… Other attractive candidates as genetic factors linking lipid metabolism, IR and GBD are
the nuclear receptors that control the expression of transporters and key enzymes of …

… , pathophysiological, and genetic influences of individual Lith genes has provided a … genetic
mechanisms of cholesterol gallstone disease in humans. Here, we summarize biliary lipid …

… lipid levels, and their potential effects on biliary disease … In our study, the effects of lipid
metabolism genes on biliary … the fact that gallstones are most closely linked to gallbladder cancer. …

… apo E, polymorphisms in other genes like apo A1, apo B, and LDL receptor and cholesterol
ester transfer protein involved in lipid metabolism have also been implicated in gallstone …

… of the human CYP7A1 gene, whereas prolonged insulin treatment induces SREBP-1c, which
inhibits human CYP7A1 gene transcription. Bile acids … FoxO1 and hepatic lipid metabolism …

… a determinant role in gene expression. This review summarizes the genes involved in biliary
salt and cholesterol synthesis, lipids transport and the Lith genes. Future studies should be …