Targeting lipid metabolism in liver cancer

M Alannan, H Fayyad-Kazan, V Trézéguet… - Biochemistry, 2020 - ACS Publications
… , implying that interfering with lipid metabolism within the tumor and the … liver cancer
patients. Therefore, this review focuses on the latest advances in drugs targeting lipid metabolism

Aberrant lipid metabolism as a therapeutic target in liver cancer

ED Pope III, EO Kimbrough, LP Vemireddy… - Expert opinion on …, 2019 - Taylor & Francis
Lipid metabolism has a role in HCC development; aberrant … Areas covered: We discuss
aberrant lipid metabolism and the … : lipids, fatty acid metabolism, lipid metabolism, liver cancer, …

Influence of liver cancer on lipid and lipoprotein metabolism

J Jiang, P Nilsson-Ehle, N Xu - Lipids in health and disease, 2006 - Springer
liver carcinogenesis. It has known that patients who suffered from acute hepatitis B could have
lipid … Furthermore, aberrations of lipid metabolism are often seen in the chronic hepatitis B …

Lipid metabolism in cancer

CR Santos, A Schulze - The FEBS journal, 2012 - Wiley Online Library
… and the abundance of lipids with signalling functions. Changes in lipid metabolism can affect
… of the alterations in lipid metabolism that have been reported in cancer, at both cellular and …

[HTML][HTML] Lipid alterations in chronic liver disease and liver cancer

B Paul, M Lewinska, JB Andersen - JHEP reports, 2022 - Elsevier
… hepatitis, and non-alcoholic fatty liver disease and steatohepatitis. Recent developments in
… primary liver cancer. Accordingly, the transcriptional landscape of lipid metabolism suggests …

SPIN1 triggers abnormal lipid metabolism and enhances tumor growth in liver cancer

M Zhao, Y Bu, J Feng, H Zhang, Y Chen, G Yang, Z Liu… - Cancer Letters, 2020 - Elsevier
… of liver cancer in vitro and in vivo and the levels of intracellular triglycerides, cholesterols
and lipid … modulates abnormal lipid metabolism and enhances growth of liver cancer through …

Lipid metabolism in development and progression of hepatocellular carcinoma

M Sangineto, R Villani, F Cavallone, A Romano… - Cancers, 2020 - mdpi.com
… More than 90% of liver cancers develop in chronic liver disease, typically associated with
viral infections, such as hepatitis B virus (HBV) and hepatitis C virus (HCV) [8]. However, the …

Lipid metabolism in cancer: New perspectives and emerging mechanisms

LA Broadfield, AA Pane, A Talebi, JV Swinnen… - Developmental cell, 2021 - cell.com
… on cancer lipid metabolism has … lipid metabolism for anti-cancer therapies is attractive,
with recent work on small-molecule inhibitors identifying compounds to target lipid metabolism. …

[HTML][HTML] Lipid metabolism in cancer: a systematic review

W Khan, D Augustine, RS Rao, S Patil… - Journal of …, 2021 - ncbi.nlm.nih.gov
lipid metabolism of cancer,” “pathways in lipid metabolism of cancer” and “biomarkers in lipid
metabolism of cancer… pathway, might be useful as therapeutics for patients with liver cancer

Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells

J Seo, DW Jeong, JW Park, KW Lee, J Fukuda… - Communications …, 2020 - nature.com
… Considering the previously reported links between lipid metabolism and tumor progression,
we hypothesized that FABP5/HIF-1α plays a crucial role in cancer development. Herein, we …