Lipid metabolism at the nexus of diet and tumor microenvironment

B Peck, A Schulze - Trends in cancer, 2019 - cell.com
… Therefore, studying the impact of diet in the development … of lipid metabolism in shaping the
tumor microenvironment (TME) and cancer cell phenotype. We will discuss how dietary lipids

The fatty acid lipid metabolism nexus in COVID-19

JE Tanner, C Alfieri - Viruses, 2021 - mdpi.com
… 2) lipid metabolic reprogramming is largely unexplored. In this review, we examine fatty acid
lipid metabolism in … that directly target the virus’s lipid dependency as well as strengthen the …

A nexus of lipid and O-Glcnac metabolism in physiology and disease

A Lockridge, JA Hanover - Frontiers in Endocrinology, 2022 - frontiersin.org
… premium on maximal uptake and storage of dietary lipids to ensure against future periods of
… activated form of LCFA important in cellular lipid metabolism. LCFA-CoA binding to purified …

Methionine metabolism in health and cancer: a nexus of diet and precision medicine

SM Sanderson, X Gao, Z Dai, JW Locasale - Nature Reviews Cancer, 2019 - nature.com
… Our group has shown that dietary MR at specific doses alters methionine metabolism in
circulation and in liver after 12 weeks in healthy mice 67 , a long-term interventional time frame …

Peroxisomes: a nexus for lipid metabolism and cellular signaling

IJ Lodhi, CF Semenkovich - Cell metabolism, 2014 - cell.com
… in lipid metabolism and their emerging role in cellular signaling relevant to metabolism. We
… the interaction of peroxisomes with lipid droplets and implications of this interaction for lipid

Lipid metabolism

NS Chandel - Cold Spring Harbor Perspectives in …, 2021 - cshperspectives.cshlp.org
… Cholesterol is not essential in our diet because most cells can generate cholesterol. The
highest producer of cholesterol is the liver, where it can be esterified into cholesterol esters, …

Nonalcoholic fatty liver disease as a nexus of metabolic and hepatic diseases

VT Samuel, GI Shulman - Cell metabolism, 2018 - cell.com
… Peripheral insulin resistance indirectly influences hepatic glucose and lipid metabolism
by … Weight loss with diet or bariatric surgery effectively treats NAFLD, but drugs specifically …

Deciphering the lipid–cancer nexus: comprehensive Mendelian randomization analysis of the associations between lipid profiles and digestive system cancer …

Y Jin, H Zhou, X Jin, J Wang - Lipids in Health and Disease, 2024 - Springer
… that alterations in lipid metabolism are closely linked to … toward less healthy Western diets
and increased consumption of … , revealing that alterations in lipid metabolism are closely linked …

[HTML][HTML] Lipid metabolism in adaptation to extreme nutritional challenges

L Olsen, E Thum, N Rohner - Developmental Cell, 2021 - cell.com
… We will first briefly review the basic functions of lipids and lipid metabolism, highlight animals
… Finally, we will discuss why humans have evolved a unique fat metabolism compared with …

A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution

A Maida, A Zota, KA Sjøberg… - The Journal of …, 2022 - Am Soc Clin Investig
Dietary protein intake is linked to an increased incidence of type 2 diabetes (T2D). Although
dietary protein dilution (DPD) can slow the progression of some aging-related disorders, …