A role of lipid metabolism during cumulusoocyte complex maturation: Impact of lipid modulators to improve embryo production

EG Prates, JT Nunes, RM Pereira - Mediators of inflammation, 2014 - Wiley Online Library
lipid reserves in the maturating oocyte [12, 13]. This review will focus on the effects of lipid
modulation by chemical molecules during oocyte … embryo development. Various aspects of …

Fatty acid composition of porcine cumulus oocyte complexes (COC) during maturation: effect of the lipid modulators trans-10, cis-12 conjugated linoleic acid (t10,c …

EG Prates, SP Alves, CC Marques, MC Baptista… - In Vitro Cellular & …, 2013 - Springer
… effect of maturation and of two lipid modulators supplementation along in vitro maturation (…
dimethylacetal (DMA) composition of porcine cumulus oocyte complexes (COC) were studied. …

… with cyclic adenosine monophosphate modulators prior to in vitro maturation alters the lipid composition and transcript profile of bovine cumulusoocyte complexes …

EM Razza, MJ Sudano, PK Fontes… - … and Development, 2018 - CSIRO Publishing
… and membrane lipid profiles have not been explored so far. Our results on cumulus cell lipid
… of the Pre-IVM oocytes at 2 h with immature oocytes, which reinforces the effectiveness of …

Regulation of fatty acid oxidation in mouse cumulus-oocyte complexes during maturation and modulation by PPAR agonists

KR Dunning, MR Anastasi, VJ Zhang, DL Russell… - PloS one, 2014 - journals.plos.org
… surge but is significantly reduced in cumulus-oocyte complexes matured in vitro. Thus we …
oxidation in cumulus-oocyte complexes could be modulated during in vitro maturation by lipid

Lipid metabolic process involved in oocyte maturation during folliculogenesis

T Liu, J Qu, M Tian, R Yang, X Song, R Li… - Frontiers in Cell and …, 2022 - frontiersin.org
… supply, respectively, promoting cumulus expansion and oocyte meiotic maturation. In addition,
as … meiosis through the MAPK/ERK signaling pathway, but it is not a key modulator in this …

Role of lipid metabolism and signaling in mammalian oocyte maturation, quality, and acquisition of competence

R Khan, X Jiang, U Hameed, Q Shi - Frontiers in cell and …, 2021 - frontiersin.org
… Hence, the removal of cumulus cells during in vitro maturation can affect lipid metabolism in
… LPA is also a major regulator of oocyte maturation by modulating the other molecules in a …

The cumulus cell layer protects the bovine maturing oocyte against fatty acid-induced lipotoxicity

F Lolicato, JF Brouwers, CHA de Lest… - Biology of …, 2015 - academic.oup.com
… of lipids in the oocyte and increased radical formation. Our results show that cumulus cells
act as a barrier, protecting oocytes … of the cumulus cells in modulating FA supply to the oocyte

Absence of cumulus cells during in vitro maturation affects lipid metabolism in bovine oocytes

S Auclair, R Uzbekov, S Elis… - American Journal …, 2013 - journals.physiology.org
… In addition, active Ser 563 -phosphorylated HSL was detected in the oocytes only after IVM,
… IVM affected lipid metabolism in the oocyte and led to suboptimal cytoplasmic maturation. …

Melatonin modulates lipid metabolism in porcine cumulusoocyte complex via its receptors

T Zhu, S Guan, D Lv, M Zhao, L Yan, L Shi… - Frontiers in cell and …, 2021 - frontiersin.org
… affects lipid biogenesis or lipolysis in porcine oocytes. In the … for monitoring lipid dynamics
in maturing porcine oocytes were … maturation of porcine oocytes through modulating the lipid

MALDI mass spectrometry reveals that cumulus cells modulate the lipid profile of in vitro-matured bovine oocytes

AA Vireque, A Tata, KRA Belaz… - Systems biology in …, 2017 - Taylor & Francis
Cumulus-oocyte complexes (COC) or denuded oocytes (DO) were matured in tissue …
modulation of the lipid profile of the oocytes according to the supplement used for the maturation