… also prone to changes in their lipid content, which hinder or … for lipid contribution in tumor
progression towards a metastatic … lipid pathways in preclinical models to slow down metastasis …

… contribution of cancer metabolism to the metastatic cascade is … in lipid metabolism that
contribute to metastasis formation in solid … by which lipids induce a pro-metastatic phenotype and …

… signaling lipids implicated in cancer migration, invasion and metastasis. Next, we summarize
the regulatory signaling hubs of lipid … to each step of metastatic formation (Fig. 3). In primary …

… Cancer cells also harness lipid metabolism to modulate the … Thus, metabolic interventions
aiming to reduce lipid availability to cancer … to prevent cancer progression and treat metastasis. …

… inhibitor strongly reduces metastatic spreading of breast cancer cells to the lungs, by
preventing the recruitment of neutrophils that promote the formation of pro-metastatic niches 29. In …

… LMW-E enhanced ACLY enzymatic activity, leading to increased lipid droplet formation for
providing cells with essential building blocks to support aggressive progression. Therefore, …

… enhancement of lipid metabolism in the different cell compartments of tumor stroma favors
metastasis formation either by proportioning lipids to fuel the aggressiveness of cancer cells (…

… in mice resulted in steatosis accompanied by increased lipid droplet formation and a reduction
in the … of cancer cells to form distant metastases. Some of the potential functions of altered …

… tissues lipids come from circulating lipids, while cancer cells … with the development of
metastasis in breast cancer (63). In … As such, a role for palmitate in the formation of membranes …

… lipid metabolic reprogramming of cancer cells at different steps along the metastatic process,
we also summarize the altered lipid … demonstrated to decrease metastatic formation in vivo, …