Lipids in cancer: a global view of the contribution of lipid pathways to metastatic formation and treatment resistance

S Vasseur, F Guillaumond - Oncogenesis, 2022 - nature.com
treatments. We also highlight the benefits of targeting lipid pathways in preclinical models
… slow down metastasis development and overcome chemo-and immunotherapy resistance. …

Lipid metabolism and resistance to anticancer treatment

N Germain, M Dhayer, M Boileau, Q Fovez, J Kluza… - Biology, 2020 - mdpi.com
… changes in lipid metabolism represent important mediators of resistance to anticancer … lipid
metabolism associated with therapy resistance, their significance and how dysregulated lipid

Lipid metabolism and endocrine resistance in prostate cancer, and new opportunities for therapy

GE Stoykova, IR Schlaepfer - International journal of molecular sciences, 2019 - mdpi.com
… Since androgens induce the accumulation of lipid droplets as … lipid droplets and support
therapy resistance. More recently, a new pathway of desaturation in PCa cells and other cancers

Adipocyte and lipid metabolism in cancer drug resistance

Y Cao - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
… involving adipocytes and lipid metabolism in altering the response to cancer treatment. In …
cancer-associated adipocytes and lipid metabolic reprogramming in cancer drug resistance

Lipids as a target for drugs modulating multidrug resistance of cancer cells

AB Hendrich, K Michalak - Current drug targets, 2003 - ingentaconnect.com
… of the membrane lipids in multidrug resistance and its … lipid phase playing active role in
many membrane processes. Along with the alterations of lipid membrane composition of cancer

Fat and furious: lipid metabolism in antitumoral therapy response and resistance

M Bacci, N Lorito, A Smiriglia, A Morandi - Trends in cancer, 2021 - cell.com
… We review mechanisms of lipid metabolism such as lipogenesis, lipid catabolism, and LD …
and resistance. Moreover, since deregulated lipid metabolism is a feature of cancer cells and …

Novel insights on lipid metabolism alterations in drug resistance in cancer

R Yang, M Yi, B Xiang - Frontiers in cell and developmental biology, 2022 - frontiersin.org
resistance. Therefore, this review compiles the current knowledge about aberrant lipid
metabolism in chemoresistant cancer, … lipid metabolism to overcome chemoresistance in cancer. …

Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles

C Peetla, S Vijayaraghavalu, V Labhasetwar - Advanced drug delivery …, 2013 - Elsevier
lipids, particularly when cancers develop acquired drug resistance, and how biophysical
changes in resistant … in membrane lipid research show the varied roles of lipids in regulating …

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

VS Viswanathan, MJ Ryan, HD Dhruv, S Gill… - Nature, 2017 - nature.com
… -induced neuroendocrine transdifferentiation in prostate cancer, and sarcomas, which are
… inhibition of a lipid peroxidase pathway as a feature of therapy-resistant cancer cells across …

Lipids in the tumor microenvironment: From cancer progression to treatment

KC Corn, MKA Windham, M Rafat - Progress in lipid research, 2020 - Elsevier
… and radiation treatments and alleviate cellular … lipids can shape each part of the cancer
lifecycle and show that there is significant potential for therapeutic intervention surrounding lipid