… insulin secretion and this stimulation was blocked by the addition of a soluble form of Wnt
receptor, secreted … lacked the Wnt-3a-stimulated insulin secretion. These data suggest that Wnt/…

… We then investigated whether Pcsk9 deficiency affects insulin production and pancreatic
β-cell function. Plasma insulin and C-peptide levels were significantly decreased in Pcsk9 KO …

… As C-peptide based indices reflect insulin secretion independent of hepatic clearance, our
results indicate lower insulin secretion in case of lesser LDL cholesterol. This could explain …

… whole body insulin sensitivity. The dose–response curve of glucose-stimulated insulin
secretion was shifted to the right in LDLR −/− islets. Significant reductions in insulin secretion in …

… added Hepatic Lipoprotein Receptor Insulin and Secretion 9605 Such receptor antibodies
are known to mimic wide spectrum secretion is containedin the cellular insulin receptor. a of …

… levels, this study investigates the effects of HDLs on insulin secretion from β-cells. … insulin
mRNA expression and insulin secretion without significantly depleting intracellular insulin or …

… density lipoprotein receptor knockout (LDLR −/− ) mice have higher cholesterol content and
secrete less insulin … cholesterol content, insulin secretion and Ca 2 + handling in these islets. …

… Hepatic lipoprotein uptake is a complex but well regulated process involving multiple …
Some particles then directly bind to the low density lipoprotein receptor (LDLR) and LDLR-related …

… /L) glucose concentrations, the insulin secretion rates induced by depolarizing agents such
… metabolism step of the insulin secretion pathway. Insulin secretion induced by the protein …

… insulin resistance, dyslipidemia, and central obesity. The low-… lipoprotein receptor-related
protein 1 (LRP1—A member of the LDL receptor family) is an endocytic and signaling receptor …