… and cumulus-oocyte complexes (COCs), which leads to a decrease in oocyte quality and …
under in vivo or in vitro conditions, alters the expression pattern of different genes related to …

… Further, ER stress and lipotoxicity have been demonstrated in liver and brain from both diet-…
lipotoxicity in other cells, we hypothesized that obesity results in the activation of lipotoxicity …

… effects to reduce the number of fixed factors, increase statistical power and allow accurate
interpretation of the complex proteomic data in combination with other functional assessments. …

… involved in lipotoxic effects induced by saturated FA exposure of cumulus-oocyte complexes
(… formation of glucosylceramides under lipotoxic-inducing conditions in COCs relates to …

… supplementation protected oocyte developmental capacity under lipotoxic conditions mainly
… to a lipotoxic microenvironment in which oocytes undergo maturation can protect oocyte …

… vivo maturation conditions. Overall … conditions, indicating that exposure to high levels of
lipids in follicle fluid is indeed inducing endoplasmic reticulum stress and potentially lipotoxicity …

… the quality of the enclosed oocyte, which relies on the … of follicular compartments and
oocyte quality. In this review, … in different pathways during oocyte final growth and maturation. …

… the oocyte to (pathophysiologically relevant) lipotoxic conditions affected subsequent embryo
development, we studied elongation, embryonic disk (ED) formation, metabolic activity and …

… by the pyruvate dehydrogenase (PDH) complex to create acetyl CoA (see … oocytes of mice
fed a high fat diet displayed a decreased MMP, as did those incubated in lipotoxic conditions …

… High fat diet in mice and obesity in women increases oocyte lipid and induces lipotoxicity
responses that could contribute to their impaired oocyte developmental competence. …