Oocyte maturation under lipotoxic conditions induces carryover transcriptomic and functional alterations during post-hatching development of good-quality blastocysts …
KLJ Desmet, WFA Marei, C Richard… - Human …, 2020 - academic.oup.com
… understanding of how the exposure of the oocyte to (pathophysiologically relevant) lipotoxic
conditions affected subsequent embryo development, we studied elongation, embryonic …
conditions affected subsequent embryo development, we studied elongation, embryonic …
Proteomic changes in oocytes after in vitro maturation in lipotoxic conditions are different from those in cumulus cells
WFA Marei, G Van Raemdonck, G Baggerman… - Scientific reports, 2019 - nature.com
… cells, they remain largely unexplored in oocytes, which have distinct organelle structure and
… bovine oocytes and cumulus cells (CCs) after in vitro maturation under lipotoxic conditions; …
… bovine oocytes and cumulus cells (CCs) after in vitro maturation under lipotoxic conditions; …
Lipotoxicity: impact on oocyte quality and reproductive efficiency in mammals
JPM Alves, M Bertolini, LR Bertolini… - Animal …, 2018 - animal-reproduction.org
… oocyte in vitro maturation medium has been shown to slow the progression of meiosis,
hampering oocyte maturation … under in vivo or in vitro conditions, alters the expression pattern of …
hampering oocyte maturation … under in vivo or in vitro conditions, alters the expression pattern of …
The cumulus cell layer protects the bovine maturing oocyte against fatty acid-induced lipotoxicity
F Lolicato, JF Brouwers, CHA de Lest… - Biology of …, 2015 - academic.oup.com
… -oocyte communication impairs bovine oocyte maturation … glucosylceramides under
lipotoxic-inducing conditions in COCs … oocyte maturation, and aberrations of the bidirectional …
lipotoxic-inducing conditions in COCs … oocyte maturation, and aberrations of the bidirectional …
Lipid metabolic process involved in oocyte maturation during folliculogenesis
T Liu, J Qu, M Tian, R Yang, X Song, R Li… - Frontiers in Cell and …, 2022 - frontiersin.org
… (PCOS) and induces lipotoxicity in oocytes, including the … Oocyte in vitro maturation
conditions are controlled by the simulation of the microenvironment to regulate oocyte maturation. …
conditions are controlled by the simulation of the microenvironment to regulate oocyte maturation. …
Role of lipid metabolism and signaling in mammalian oocyte maturation, quality, and acquisition of competence
R Khan, X Jiang, U Hameed, Q Shi - Frontiers in cell and …, 2021 - frontiersin.org
… poor or rich metabolic conditions such as imbalance … oocyte maturation, growth and oocyte
competence acquisition. To understand the role of lipids in controlling the oocyte development…
competence acquisition. To understand the role of lipids in controlling the oocyte development…
High-fat diet causes lipotoxicity responses in cumulus–oocyte complexes and decreased fertilization rates
… Further, ER stress and lipotoxicity have been demonstrated in liver and brain from both diet-…
lipotoxicity in other cells, we hypothesized that obesity results in the activation of lipotoxicity …
lipotoxicity in other cells, we hypothesized that obesity results in the activation of lipotoxicity …
[PDF][PDF] … cells protect the bovine oocyte against lipotoxicity by converting saturated into unsaturated fatty acids using stearoyl-CoA-desaturase during in vitro maturation
H Aardema, HTA Van Tol… - Anim …, 2016 - host-article-assets.s3.amazonaws …
… We assessed meiotic and cytoplasmic oocyte maturation, in … In our conditions, combination
of 50 ng/mL EGF, 100 ng/mL … pig oocytes since it offers superior results of oocyte maturation …
of 50 ng/mL EGF, 100 ng/mL … pig oocytes since it offers superior results of oocyte maturation …
[HTML][HTML] Exposure to lipid-rich follicular fluid is associated with endoplasmic reticulum stress and impaired oocyte maturation in cumulus-oocyte complexes
… with in vivo maturation conditions. … conditions, indicating that exposure to high levels of
lipids in follicle fluid is indeed inducing endoplasmic reticulum stress and potentially lipotoxicity …
lipids in follicle fluid is indeed inducing endoplasmic reticulum stress and potentially lipotoxicity …
Alpha-linolenic acid protects the developmental capacity of bovine cumulus–oocyte complexes matured under lipotoxic conditions in vitro
WFA Marei, J De Bie, O Mohey-Elsaeed… - Biology of …, 2017 - academic.oup.com
… (ALA) during in vitro oocyte maturation (IVM) in the presence of PSO on subsequent embryo
… supplementation protected oocyte developmental capacity under lipotoxic conditions mainly …
… supplementation protected oocyte developmental capacity under lipotoxic conditions mainly …
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