… -induced lipotoxicity in other cells, we hypothesized that obesity results in the activation of
lipotoxicity … , and apoptosis occur in ovarian cells and the oocyte in response to a high-fat diet. …

… in vivo [12] and therefore to analyze the responses of cumulus cells to these conditions. The
… involved in lipotoxic effects induced by saturated FA exposure of cumulus-oocyte complexes …

… Therefore, the aim of this study was to analyze and compare cellular responses to PA-induced
lipotoxicity during in vitro maturation of bovine COCs using shotgun proteomic analysis of …

… granulosa cells and cumulus-oocyte complexes (COCs), which leads to a decrease in …
regard to the effects of lipotoxicity on oocyte quality. Lipotoxicity and reproductive response …

… inducing endoplasmic reticulum stress and potentially lipotoxicity responses. It is likely that
… in cumulus cells, as oocytes are transcriptionally inactive at this stage and because cumulus …

… maturation, in terms of cortical granules (CG) and mitochondrial distribution, apoptotic rate
and steroidogenic response of cumulus-oocyte-complexes (COCs) after IVM. A pool of 500 …

… (UPR) and protein translation may be different in oocytes than in somatic cells. … -induced
stress responses in oocytes to those in cumulus cells (CC). We exposed bovine cumulus-oocyte …

… oocyte developmental capacity under lipotoxic conditions mainly by protecting cumulus cell
… Thus, the alteration in cumulus cell expansion in response to PSO and ALA can be directly …

… the oocytes from lipotoxicity under the excess of FA in culture media. Results of the present
experiment revealed a distinct response of the oocyte and corresponding cumulus cells to …

… to elevated glucose leads to high intracellular levels of free fatty acids that trigger lipotoxicity…
and oocyte quality in association with lipotoxicity responses in cumulus-oocyte complexes (…