… -induced lipotoxicity in other cells, we hypothesized that obesity results in the activation of
lipotoxicity … , and apoptosis occur in ovarian cells and the oocyte in response to a high-fat diet. …

… granulosa cells and cumulus-oocyte complexes (COCs), which leads to a decrease in …
regard to the effects of lipotoxicity on oocyte quality. Lipotoxicity and reproductive response …

… lipotoxicity responses. It is likely that the observed changes in gene expression reflect alterations
in cumulus cells, as oocytes are … reticulum stress responses are occurring in the oocyte, …

… cellular responses to PA-induced lipotoxicity during in … lipotoxic effects to reduce the number
of fixed factors, increase statistical power and allow accurate interpretation of the complex …

… High fat diet in mice and obesity in women increases oocyte lipid and induces lipotoxicity
responses that could contribute to their impaired oocyte developmental competence. …

… involved in lipotoxic effects induced by saturated FA exposure of cumulus-oocyte complexes
(… intermediate responses when compared to control oocytes and to oocytes exposed to the …

… In other tissues, obesity leads to lipotoxicity responses including … lipotoxicity occurs in the
cumulus–oocyte complexes of obese mice and in the ovarian cells of women. Thus lipotoxicity …

… by which oocytes can sense and respond to stress are not … due to lipotoxicity, oxidative
stress, and heat stress on oocyte … mechanisms in whole cumulus-oocyte complexes (COCs) can …

… and oocyte quality in association with lipotoxicity responses in cumulus-oocyte complexes
(… intracellular lipid accumulation and altered mitochondrial activity in oocytes (16, 17), as well …

… -linolenic acid (ALA) during in vitro oocyte maturation (IVM) in the presence of … Bovine
cumulus–oocyte complexes (COCs) were … protected oocyte developmental capacity under …