… -induced lipotoxicity, which lead to developmental arrest [4]. Similar events have been
reported during in vivo oocyte maturation, wherein cumulus–oocyte complexes (COCs) exposed …

… development [59], an elevated fatty acid concentration in the FF has a lipotoxic effect that
leads to the apoptosis of cumulus cells and reactive oxygen production, adversely affecting …

… these lipoprotein complexes to the cumulus oocyte complex. … negative cascade of lipotoxic
responses induced by saturated … saturated FFA induce lipotoxic responses of granulosa cells …

… microscopy in bovine cumulus-oocyte complexes (COCs) treated with specific … response to
CPT1 inactivation. In skeletal muscles, activation of FAO in vitro allowed overriding of lipotoxic …

… ability to counteract oxidative stress in cumulus-oocyte complexes (COCs) exposed to hydrogen
… follicular environment in response to obesity. Lipotoxicity is a cellular response to a high …

… Cumulus-oocyte-complexes (COCs) were retrieved from … multiparous) on estrous response
and time of ovulation in … goats neither for estrus nor for ovulation response (100 vs. 92%, …

… instance apolipoprotein complexes such … lipotoxicity response in ovarian cells and oocytes.
Excess lipid is present in follicle fluid of obese women and in the cumulus cells and oocytes …

… Wu LL, Dunning KR, Yang X, Russell DL, Lane M, Norman RJ & Robker RL 2010 High-fat
diet causes lipotoxicity responses in cumulus–oocyte complexes and decreased fertilization …

… follicle, oocytes are enclosed within a cumulus, forming a cumulus-oocyte complex (COC). …
A part of the CCs had visible cytoplasmic LDs, which are colored in brown by reaction with …

… production of bovine cumulus–oocyte complexes (COCs), this … is required when lipotoxicity
is present in the oocyte, as the … the formula are linked to the response observed in this study. …