Palmitic acid in chicken granulosa cell death-lipotoxic mechanisms mediate reproductive inefficacy of broiler breeder hens

YL Xie, YE Pan, CJ Chang, PC Tang, YF Huang… - Theriogenology, 2012 - Elsevier
… aberrations associated with poor egg production in broiler … Palmitic acid was supplemented
as a complex with 5% fatty … Primer concentrations in the final reaction were 300 nM for …

Metabolic control of oocyte development: linking maternal nutrition and reproductive outcomes

L Gu, H Liu, X Gu, C Boots, KH Moley… - Cellular and molecular life …, 2015 - Springer
oocyte development is a complex process regulated by a vast number of intra- and extra-ovarian
factors. Oocytes … from oogonia into primary oocytes [1–3]. Around the time of birth, …

Lipid availability during in vitro maturation alters oocyte lipid content and blastocyst development and metabolism

CB de Lima, GZ Barbosa, J Ispada… - … in Domestic Animals, 2023 - Wiley Online Library
Oocytes and embryos were analysed by Multiple Reaction Monitoring mass spectrometry
(… Cumulus-oocyte complexes (COCs; n = 30 COCs per group in seven replicates) were …

An overview on how cumulus cells interact with the oocyte in a condition with elevated NEFA levels in dairy cows

H Aardema, HTA van Tol, PLAM Vos - Animal Reproduction Science, 2019 - Elsevier
… -oocyte-complex responds on his NEFA environment. … Although in first instance the response
of the oocyte to … to prevent a lipotoxic impact by saturated NEFA on the oocyte. However, in …

Studies on energy metabolism–related lipid compositions in blood and oocytes at different lactation stages in dairy cows

古川瑛理 - 2023 - eprints.lib.hokudai.ac.jp
… The objective of the present study was to obtain insights into lipotoxicity in oocytes of the …
High-fat diet causes lipotoxicity responses in cumulus-oocyte complexes and decreased …

Ovarian Cell Biology Group

R Robker, M Barry, R Rose, LL Wu, M Lane - Discipline of Paediatrics & …, 2014 - Citeseer
… , Lane M, Norman RJ, Robker RL High fat diet causes lipotoxicity responses in cumulus-oocytecomplexes
and decreased fertilization rates Endocrinology. 2010 Nov; 151 (11): 5438-45. …

Identification of perilipin-2 as a lipid droplet protein regulated in oocytes during maturation

X Yang, KR Dunning, LLY Wu, TE Hickey… - Reproduction …, 2010 - CSIRO Publishing
… cumulus–oocyte complexes (COCs) with BODIPY 493/503, were small and diffuse in oocytes
of preovulatory COCs, but larger and more centrally located after maturation in response to …

High-fat-diet impaired mitochondrial function of cumulus cells but improved the efficiency of parthenogenetic embryonic quality in mice

J Li, S Wang, B Wang, H Wei, X Liu, J Hao… - Animal Cells and …, 2018 - Taylor & Francis
… Cumulus-oocyte complexes (COCs) were collected from the … real-time quantitative polymerase
chain reaction (RT-PCR) and … of energy from high-fat diet before appearing as lipotoxicity. …

[HTML][HTML] The impact of unbalanced maternal nutritional intakes on oocyte mitochondrial activity: implications for reproductive function

G Fabozzi, B Iussig, D Cimadomo, A Vaiarelli… - Antioxidants, 2021 - mdpi.com
… suffering from lipotoxicity, namely intracellular lipid accumulation, inflammatory response, and
… with abnormal cumulus–oocyte complex morphology [47]. However, studies using human …

Overfeeding-induced ovarian dysfunction in broiler breeder hens is associated with lipotoxicity

SE Chen, JP McMurtry, RL Walzem - Poultry science, 2006 - Elsevier
… morphology, and egg production in response to acute voluntary … severity of lipotoxic metabolic
and hormonal responses among … Effective improvement of this complex trait may be best …