Simultaneous determination of matrine, sophoridine and oxymatrine in Sophora Flavescens Ait. by high performance liquid chromatography

K Li, H Wang - Biomedical Chromatography, 2004 - Wiley Online Library
… for the determination of alkaloids in Sophora flavescens Ait. The method has been
successfully applied to the simultaneous determination of matrine, oxymatrine and sophoridine in …

Determination and pharmacokinetic study of oxymatrine and its metabolite matrine in human plasma by liquid chromatography tandem mass spectrometry

X Wu, T Hang, J Shen - … of pharmaceutical and biomedical analysis, 2006 - Elsevier
… There is little information about the pharmacokinetics of oxymatrine (OMT) … liquid
chromatography tandem mass spectrometry (LC–MS/MS) method was established for the …

Determination of Matrine and Oxymatrine in Sophora Flavescens Ait. via High Performance Liquid Chromatography

YA Jung, X Wan, H Yan, KH Row - … of Liquid Chromatography & …, 2008 - Taylor & Francis
liquid chromatographic method (HPLC) has been developed and validated for analysis of
matrine and oxymatrine in … were 3.3% for the matrine and 2.9% for the oxymatrine analysis. …

Pharmacokinetic study of matrine, oxymatrine and oxysophocarpine in rat plasma after oral administration of Sophora flavescens Ait. extract by liquid chromatography …

L Zhang, W Liu, R Zhang, Z Wang, Z Shen… - … and biomedical analysis, 2008 - Elsevier
liquid chromatography tandem mass spectrometric method (HPLC-MS) has been developed
and validated for the simultaneous determination of matrine (MT), oxymatrine (… liquidliquid

… of oxymatrine and its active metabolite matrine in human plasma after administration of oxymatrine oral solution by high-performance liquid chromatography coupled …

R Fan, R Liu, R Ma, K Bi, Q Li - Fitoterapia, 2013 - Elsevier
determined a specific and sensitive liquid chromatography mass spectrometry (LC-MS)
method of OMT and its active metabolite MT after administration of oxymatrine … fast liquid-liquid

Determination of oxymatrine and its metabolite matrine in rat blood and dermal microdialysates by high throughput liquid chromatography/tandem mass spectrometry

H Zheng, G Chen, L Shi, Z Lou, F Chen, J Hu - … and biomedical analysis, 2009 - Elsevier
Oxymatrine (OMT) and matrine (MT) are the major quinolizidine alkaloids found in certain
Sophora plants, which have been extensively used in China for the treatment of viral hepatitis, …

Simultaneous determination of oxymatrine and its active metabolite matrine in dog plasma by liquid chromatography–mass spectrometry and its application to …

S Wang, G Wang, X Li, J Sun, R Ma, L Sheng - Journal of Chromatography …, 2005 - Elsevier
… Therefore, we developed a simple, sensitive high performance liquid chromatography–mass
spectrometry (LC–MS) method for the simultaneous determination of OMT and MT in …

Determination of oxymatrine in Sophora Radix by high performance liquid chromatography

SK Yang, YJ Yun, MO Namgung - Analytical Science and …, 2004 - koreascience.kr
… Abstract:A high performance liquid chromatographic method was designed for the quantitative
analysis of oxymatrine in Sophora Radix. The separation of oxymatrine was performed by …

Dispersive liquidliquid microextraction combined with high-performance liquid chromatography for the simultaneous analysis of matrine alkaloids in traditional …

R Zhang, S Hu, X Chen, X Bai - Journal of chromatographic …, 2016 - academic.oup.com
liquidliquid microextraction (DLLME), coupled with high-performance liquid chromatography
… extraction and determination of the trace level matrine alkaloids (oxymatrine, matrine, …

Determination of oxymatrine in human plasma by LC-MS and study on its pharmacokinetics

W Zhang, B Xiang, P Ma - Journal of chromatographic science, 2008 - academic.oup.com
… A sensitive and selective liquid chromatographic–mass spectrometric method is built to
determine oxymatrine in human plasma. After a liquidliquid extraction for samples, samples are …