… Activation of the PI3K/Akt/mTOR pathway is an important signaling mechanism involved
in the development and the progression of liver cancer stem cell (LCSC) population during …

… the drug resistance of HCC cells. Liver cancer stem cells (LCSCs), also known as liver
tumor-initiating cells, represent one small subset of cancer cells that are responsible for disease …

… HOTAIR accelerates Human liver cancer stem cell (hLCSC) malignant … liver cancer cells
malignant proliferation, we established the stable human liver cancer stem cell (hLCSC) cell …

… MCM7 is downregulated in ATO-treated cancer cells We then addressed the question of
how ATO regulates liver cancer cells. We first investigated ATO-induced molecular alterations …

… However, their roles in the chemoresistance in liver cancer stem cells … liver cancer stem
cells to doxorubicin, the most frequently used chemotherapeutic agent in treating liver cancer. …

… Significant progress has been made in liver stem cell and liver cancer stem cell research
in the last 2 years. Although normal and cancerous liver stem cells or LPCs naturally share …

… liver cancer and is an important medical problem [1]. Recent studies have demonstrated that
liver … of undifferentiated cancer stem cells (CSCs) or termed tumor-initiating cells (TICs) [2]. …

Liver and biliary tract cancers are highly aggressive, are heterogeneous in their phenotypic …
Cancers have subpopulations of cells termed “cancer stem cells” (CSCs) that share common …

… cell adhesion molecule (EpCAM) [5], it has proven possible to differentiate between liver
cancer stem cells (LCSC) and liver cancer cells. … treatment in clinical liver cancer therapy. The …

… of cells with enhanced tumorigenicity and chemoresistance that are called cancer stem (or
stem-like) cells. … regulation and DNA damage responses in EpCAM + liver cancer stem cells. …