… The unfolded protein response (UPR) is a protective cellular response activated under … in
several forms of liver disease including nonalcoholic fatty liver disease (NAFLD). Recent data …

… Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease in North
America. The clinical-histologic spectrum of NAFLD extends from a nonalcoholic fatty liver (…

… causes of nonalcoholic fatty liver disease (NAFLD) are … observed in liver and adipose tissue
of humans with NAFLD and/or … and the unfolded protein response in the context of NAFLD. …

… fatty liver disease is a major public health burden. Although many features of nonalcoholic
fatty liver disease … imaging characteristic of nonalcoholic fatty liver disease is the accumulation …

… With no approved pharmacological treatment, nonalcoholic fatty liver disease (NAFLD) is
now the most common cause of chronic liver disease in Western countries and its worldwide …

… the physiological client protein load and suppressing apoptosis in hepatocytes, and they
support the pathological role of ER stress in the evolution of fatty liver disease under adverse …

… liver disease (ALD). However, the mechanisms by which ethanol elicits these cellular responses
… that activation of the unfolded protein response (UPR) in response to secretory pathway …

… , unfolded proteins accumulates within the ER. The unfolded protein response (UPR) is a
fundamental cellular process that is triggered by the accumulation of unfolded proteins within …

… reticulum and the unfolded protein response in the context of nonalcoholic fatty liver …
reticulum and the unfolded protein response in the context of nonalcoholic fatty liver disease. …

… The unfolded protein response (UPR) is activated upon the accumulation of misfolded proteins
in the … protein (BiP)/glucose-regulated protein 78 (GRP78). The accumulation of unfolded …