过去一年中添加的文章，按日期排序
[HTML][HTML] Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related …
L Xiao, Y Li, C Hong, P Ma… - Journal of …, 2024 - … -medicine.biomedcentral.com
3 天前 - … To explore the genetic association of SNPs with phenotypes, we analyzed
autosomal SNPs and identified 114 conditionally independent signals associated with MASLD …
autosomal SNPs and identified 114 conditionally independent signals associated with MASLD …
[HTML][HTML] Non-Alcoholic Fatty Liver Disease Induced by Feeding Medium-Chain Fatty Acids Upregulates Cholesterol and Lipid Homeostatic Genes in Skeletal Muscle …
4 天前 - … Non-alcoholic fatty liver disease (NAFLD) is a range of disorders characterized by
lipid … Our objective was to determine the association between NAFLD and the skeletal muscle …
lipid … Our objective was to determine the association between NAFLD and the skeletal muscle …
[HTML][HTML] Low HDL-C/ApoA-I index is associated with cardiometabolic risk factors and coronary artery calcium: a sub-analysis of the genetics of atherosclerotic disease …
GC Cardoso-Saldaña, NE Antonio-Villa… - BMC Endocrine …, 2024 - Springer
5 天前 - … This study aimed to investigate the association between the HDL-C/ApoA-I
index with cardiometabolic risk factors and subclinical … Non-alcoholic fatty liver disease …
index with cardiometabolic risk factors and subclinical … Non-alcoholic fatty liver disease …
[HTML][HTML] … integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease
5 天前 - … association studies (GWASs) have identified abdominal obesity loci that harbor
genes … to lead to metabolic dysfunction-associated steatotic liver disease (MASLD). However, …
genes … to lead to metabolic dysfunction-associated steatotic liver disease (MASLD). However, …
Expanding the phenotypic spectrum of CC2D2A-related ciliopathies: a rare homozygous nonsense variant in a patient with suspected nephronophthisis
ZT Sentell, ZW Nurcombe, L Mougharbel… - … of Human Genetics, 2024 - nature.com
5 天前 - … NGS of genes associated with cystic and interstitial renal disease (Supplementary
Table S1) identified a homozygous nonsense variant in the gene CC2D2A: NC_000004.12:g.…
Table S1) identified a homozygous nonsense variant in the gene CC2D2A: NC_000004.12:g.…
A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins
S Sharapov, A Timoshchuk, O Zaytseva, D Maslov… - medRxiv, 2024 - medrxiv.org
5 天前 - … These genes are predominantly expressed in the liver and show previously unknown
genetic link between plasma protein N-glycosylation, metabolic and liver diseases, and …
genetic link between plasma protein N-glycosylation, metabolic and liver diseases, and …
[HTML][HTML] Associations between modifiable risk factors and hepatocellular carcinoma: a trans-ancestry Mendelian randomization study
X Wei, C Yang, Q Lin, M Qiu, Q Wen, Z Zhou, Y Jiang… - BMC cancer, 2024 - Springer
5 天前 - … In East Asians, genetic association of HCC was … liver diseases, including MASLD
[41] and fibrosis [42]. In our study, we observed a positive association between genetically …
[41] and fibrosis [42]. In our study, we observed a positive association between genetically …
Association between primary biliary cholangitis with diabetes and cardiovascular diseases: a bidirectional multivariable Mendelian randomization study
YL Lin, T Yao, YW Wang, JS Yu, C Zhen, JF Lin… - Clinics and Research in …, 2024 - Elsevier
6 天前 - … is an autoimmune liver disease characterized by damage … by the European
Association for the Study of the Liver (Table … cohorts in the genetic associations. Specific …
Association for the Study of the Liver (Table … cohorts in the genetic associations. Specific …
The multifaceted functions of NFE2L1 in metabolism and associated disorders
X Zhao, C Xu, Y Ding, N Yan - Life Sciences, 2024 - Elsevier
6 天前 - … adipogenic and lipolysis genes in both liver and adipose … genes expression, which
dysfunction has been related with multiple diseases including neurodegenerative diseases, …
dysfunction has been related with multiple diseases including neurodegenerative diseases, …
Discovery of a novel homocysteine thiolactone hydrolase and the catalytic activity of its natural variants
S Hou, H Liu, Y Hu, J Zhang, X Deng, Z Li… - Protein …, 2024 - Wiley Online Library
6 天前 - … In conclusion, toxic HTL is a natural substrate of the abundant liver … association
of specific SNPs with increased risk for HTL-associated CVD and neurodegenerative disease. …
of specific SNPs with increased risk for HTL-associated CVD and neurodegenerative disease. …