… from chronic HBV infection, we recently identified a benefit of 9-month IFN-γ treatment
resulting in decreased fibrosis scores and a reduced number of α-smooth muscle actin-positive …

… in patients with viral hepatitis that cannot be fully explained by ethanol-enhanced liver …
liver fibrosis: inhibition of the antifibrotic effects of natural killer (NK) cells and interferon-γ (IFN-γ). …

… degrees of liver diseases. In the present study, we compared the antifibrotic efficacy of NK
cells/IFN-c on early and advanced liver fibrosis in vivo and the effects of NK cells/IFN-c on the …

… of proliferating HSC in early stages of liver the role of transformed HSC in liver fibrosis and
the specific effect of IFN-g in reducing this process. fibrosis. The final result is the formation of …

… IFNγ to the liver myofibroblasts. For that, we altered the cell binding properties of IFNγ, by
delivery of the IFNγ… interferon γ). In recent years, we demonstrated that HSC-specific delivery of …

… CDE-induced hepatic fibrosis in IFNγ-treated mice. We observed increased liver collagen
content and an accelerated and augmented hepatic stellate cell response with IFNγ-treatment …

… In summary, IFN-γ has significant beneficial effects on liver fibrosis in patients with chronic
HBV infection. Moreover, our data indicate that IFN-γ antagonizes the TGF-β/Smad pathway, …

… The IFN-γ +3810 A allele was associated with a reduced risk of PPF. The number of … IFN-γ
polymorphisms with severe fibrosis (IFN-γ +2109, p = 0.05, OR = 0.39, CI = 0.15–1.03; IFN-γ +…

… Interferon gamma was infused continuously by osmotic pump during the induction of liver
fibrosis, after which lipocytes were … Finally, whole liver type I collagen mRNA was quantitated. …

… + CD4 + T cells can produce abundant IFN-γ and IL-17, both of which play a role in liver
fibrogenesis, 4, 17 There are no available data on CD161 + CD4 + T cells in liver fibrosis. …