The effect of CYP1A induction on amiodarone disposition in the rat

ME Elsherbiny, DR Brocks - Journal of pharmaceutical sciences, 2010 - Elsevier
… In the treatment of cardiac arrhythmias, amiodarone (AM) has emerged as a primary
therapeutic agent. In addition to other cytochrome P450 (CYP), 1A1 and 1A2 facilitate the …

[HTML][HTML] Real time identification of drug-induced liver injury (DILI) through daily screening of ALT results: a prospective pilot cohort study

…, Drug Induced Liver Injury Groupe Hospitalier Pitié … - 2012 - journals.plos.org
… All patients period had ALT elevation after history of drug intake. In the group of patients who
… Among our identified DILI, we acknowledge that the benefit-risk of stopping amiodarone is …

Side effects of long-term amiodarone therapy.

L Harris, WJ McKenna, E Rowland, DW Holt… - Circulation, 1983 - Am Heart Assoc
… 13 Each 200mg tablet of amiodarone contains approximately 75 mg of … of amiodarone
yields 9 mg/day of iodine,16 which represents a 100-fold increase over the normal iodine intake. …

Drug-induced liver injury associated with statins

MW Russo, M Scobey… - Seminars in Liver …, 2009 - thieme-connect.com
… A weight-loss diet with restricted carbohydrate intake and … hepatotoxic medication use
including amiodarone, diltiazem, … Because both amiodarone and diltiazem are competitive …

[HTML][HTML] Chronic drug-induced liver injury: updates and future challenges

Q Wang, A Huang, JB Wang, Z Zou - Frontiers in Pharmacology, 2021 - frontiersin.org
Chronic drug-induced liver injury (DILI), defined as DILI with persistent liver injury more than
one year after the first onset by the latest European guidelines, is a notable challenge …

The burden of acute nonfulminant drug-induced hepatitis in a United States tertiary referral center

MV Galan, JA Potts, AL Silverman… - Journal of clinical …, 2005 - journals.lww.com
… %), while amiodarone was the single agent most commonly associated with liver injury (7 of
… Antibiotics and amiodarone were the most common drug culprits in our population. Time to …

Drug‐induced liver disease

S Chitturi, GC Farrell - Schiff's diseases of the liver, 2011 - Wiley Online Library
… ) relating the drug intake and liver test abnormality are … liver injury, or when one or more
of the functions of the liverAmiodarone, etretinate, ketoconazole, and hypervitaminosis …

Effect of grapefruit juice on amiodarone induced nephrotoxicity in albino rats

SA Sakr, EM El-Gamal - Toxicology and industrial health, 2016 - journals.sagepub.com
Amiodarone is a potent antiarrhythmic drug that is used to … of amiodarone on the kidney of
albino rats and the possible ameliorative role of grapefruit juice. Administration of amiodarone

[PDF][PDF] Amiodarone‐induced hepatic phospholipidosis: Correlation of morphological and biochemical findings in an animal model

M Pirovino, O Müller, T Zysset, U Honegger - Hepatology, 1988 - Wiley Online Library
… the effects of amiodarone on the liver in an animal … amiodarone in a concentration of 2.12
gm per kg of food (NAFAG) were investigated. This dose, resulting in a daily amiodarone intake

Drug metabolism, drug interactions, and drug-induced liver injury in living donor liver transplant patients

S Ganesh, OA Almazroo, A Tevar, A Humar… - Clinics in liver …, 2017 - liver.theclinics.com
… (I/R) injury on hepatic drug metabolism in LDLT recipients is expected to be lower than in
DDLT recipients, injury of the liver following warm I/R still occurs. The warm I/R injury can …