Liver injury and disease pathogenesis in chronic hepatitis C

D Yamane, DR McGivern, T Masaki… - Hepatitis C virus: from …, 2013 - Springer
… ineffective immune response to the virus that causes liver injury, but fails to eliminate the
infection (see chapter "Adaptive Immune Responses in Hepatitis C Virus Infection" by Neumann-…

Mechanisms of liver cell injury in acute and chronic hepatitis B

M Mondelli, ALWF Eddleston - Seminars in liver disease, 1984 - thieme-connect.com
… course or progress to chronic hepatitis is still poorly … hepatitis transmission studies in
volunteers4>5 in which the development of a chronic carrier state in some, and severe hepatitis in …

Mechanisms of viral hepatitis induced liver injury

Y Nakamoto, S Kaneko - Current molecular medicine, 2003 - ingentaconnect.com
chronic hepatitis. During the course of persistent infection, continuous intrahepatic inflammation
maintains a cycle of liver … progression of liver disease, the mechanisms of liver injury in …

Apoptosis: a mechanism of acute and chronic liver injury

ME Guicciardi, GJ Gores - Gut, 2005 - gut.bmj.com
… failure (mediated by Fas agonistic agents) or acute viral hepatitis. Moreover, the same … from
fulminant hepatitis, and prevent development of fibrosis in a model of chronic hepatitis. As a …

Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury

MJ Walsh, DM Vanags, AD Clouston… - …, 2004 - Wiley Online Library
… to liver injury remain uncertain. We studied 125 patients with chronic hepatitis C to assess the
effect of steatosis on liverliver cell apoptosis and disease severity. A significant increase in …

Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1–associated cytokines

J Napoli, GA Bishop, PH McGuinness, DM Painter… - Hepatology, 1996 - journals.lww.com
… The liver specimens in this study were classified into three 5 … groups, namely chronic
hepatitis C (n Å 13), chronic hepatitis … the findings in this study suggest that in chronic hepatitis

Prevalence and risk factors of hepatic steatosis and its impact on liver injury in Chinese patients with chronic hepatitis B infection

J Shi, J Fan, R Wu, X Gao, L Zhang… - Journal of …, 2008 - Wiley Online Library
… of hepatic steatosis in chronic hepatitis B infection (CHB) is unclear… in patients with CHB and
its relationship with liver injury. … liver injury in 1915 patients with chronic hepatitis B infection. …

[PDF][PDF] Hypercytolytic activity of hepatic natural killer cells correlates with liver injury in chronic hepatitis B patients

Z Zhang, S Zhang, Z Zou, J Shi, J Zhao, R Fan… - …, 2011 - Wiley Online Library
… -associated acute-onchronic liver failure.Although these … in liver injury, NK cells may also
use some other ligands to mediate liver injury in various disease progression phases of chronic

Caspase activation correlates with the degree of inflammatory liver injury in chronic hepatitis C virus infection

H Bantel, A Lügering, C Poremba, N Lügering, J Held… - Hepatology, 2001 - Elsevier
… is involved in HCV-associated liver injury. Moreover, measurement of caspase activity may
represent a reliable marker for the early detection of liver damage, which may open up new …

Fat, diabetes, and liver injury in chronic hepatitis C

V Ratziu, JB Trabut, T Poynard - Current gastroenterology reports, 2004 - Springer
… in patients infected by the hepatitis C virus (HCV), are often present in patients … chronic
hepatitis C. Both conditions result in fatty liver, which in turn is associated with more severe liver