Systematic elucidation of the potential mechanism of Erzhi pill against drug‐induced liver injury via network pharmacology approach

S Huang, F Mu, F Li, W Wang, W Zhang… - Evidence‐Based …, 2020 - Wiley Online Library
Erzhi pill (EZP) on drug-induced liver injury (DILI). Methods. At first, we collected information
of bioactive compounds of EZP from Traditional Chinese Medicine Systems Pharmacology …

Erzhi Pill® Protected Experimental Liver Injury Against Apoptosis via the PI3K/Akt/Raptor/Rictor Pathway

HM Zhao, XY Zhang, XY Lu, SR Yu, X Wang… - Frontiers in …, 2018 - frontiersin.org
… (EZP) is one of the basic prescriptions for treating liver … of liver disease. To define the
mechanism of the hepatoprotective effect of EZP in the treatment of liver disease, hepatic injury

Erzhi Pill® repairs experimental liver injury via TSC/mTOR signaling pathway inhibiting excessive apoptosis

B Zhou, H Zhao, X Lu, X Wang, Y Zou… - Evidence‐Based …, 2017 - Wiley Online Library
Erzhi Pill (EZP) on the liver injury via observing TSC/mTOR signaling pathway activation. The
experimental liver injury … EZP treated 2-AAF/PH-induced liver injury by the therapeutic and …

Preventive effect and mechanism of Erzhi pills against acute liver injury induced by carbon tetrachloride in mice.

DLX Duan LengXin, GY Gao Yang, HJ Hu Ju… - 2018 - cabidigitallibrary.org
… <0.01) in Erzhi pill groups. The … liver were significantly decreased in Erzhi pill 2.8 and 5.6
g.kg -1 groups (P<0.05). The result of TUNEL assay showed that the apoptosis rates in Erzhi pill

Erzhi Pill Protects Against Hepatic Ischemia/Reperfusion Injury Through Activating PI3K/Akt/SIRT1 Signaling Pathway

W Li, H Chen, Z Li, D Hu, Y Liu, S Huang, S Hu, J Chen… - papers.ssrn.com
liver injury, alcohol liver injury and drug liver injury. However, … Erzhi pill alleviated hepatic
ischemia-reperfusion injury in … in liver protection from erzhi wan on acute hepatic injury 29 …

A Network‐Based Approach to Explore the Mechanism and Bioactive Compounds of Erzhi Pill against Metabolic Dysfunction‐Associated Fatty Liver Disease

S Huang, F Mu, F Li, W Wang, H Chen… - Journal of Diabetes …, 2020 - Wiley Online Library
… the primary cause of end-stage liver disease [4]. Therefore, … Erzhi pill (EZP) is a TCM used
for liver disease in the past … 1 : 1 and functions as a liver and kidney tonic in traditional Chinese …

Literature Review of Traditional Chinese Medicine Herbs–Induced Liver Injury From an Oncological Perspective With RUCAM

HC Chow, TH So, HCW Choi… - Integrative Cancer …, 2019 - journals.sagepub.com
… interactions between Chinese and Western drugs that may lead to hepatotoxicity. There have
been numerous reports of liver injury caused by TCM herbs and concoctions. However, the …

[PDF][PDF] The anti-tumor effect of Erzhi pills on breast cancer cell MCF-7 and the intervention in endocrine therapy adverse reactions

Q Liu, LL Li, CH Xu, GQ Zhang, Z Sun… - TMR Theory and …, 2019 - tmrjournals.cn
… the potential ability of medicated serum of Erzhi pills on growth, proliferation and … Erzhi
pills can antagonize damage and protect liver function of antioxidant action [7]. Erzhi pills

Integrative pharmacology reveals the mechanisms of Erzhi Pill, a traditional Chinese formulation, against diabetic cardiomyopathy

M Peng, T Xia, Y Zhong, M Zhao, Y Yue, L Liang… - Journal of …, 2022 - Elsevier
Erzhi Pill (EZP) is a traditional Chinese prescription that has marked effects in treating
type 2 diabetes mellitus and diabetic nephropathy. However, its underlying pharmacological …

Are the release characteristics of Erzhi pills in line with traditional Chinese medicine theory? A quantitative study

J Zuo, C Park, M Doschak, R Löbenberg - Journal of integrative medicine, 2021 - Elsevier
… Study of active components with immunoregulation from Erzhi Pill on lymphocytes and
macrophages in mice. Shi Zhen Guo Yi Guo Yao 2006;17(10):1921–3 [Chinese with abstract in …