[HTML][HTML] Human liver stem cell-derived extracellular vesicles prevent aristolochic acid-induced kidney fibrosis

S Kholia, MB Herrera Sanchez, M Cedrino… - Frontiers in …, 2018 - frontiersin.org
… played a protective role by alleviating interstitial fibrosis in a mouse model of unilateral ureter
obstruction (2). Human liver stem cells (HLSCs), a stem cell population resident in the liver, …

[HTML][HTML] Human liver stem cell derived extracellular vesicles alleviate kidney fibrosis by interfering with the β-catenin pathway through miR29b

S Kholia, MB Herrera Sanchez, MC Deregibus… - International Journal of …, 2021 - mdpi.com
… In order to investigate whether the up-regulation of β-catenin is a key factor in causing
renal fibrosis, we investigated the expression of β-catenin in mouse kidney cortical fibroblasts (…

[HTML][HTML] Chronic kidney disease after liver, cardiac, lung, heart–lung, and hematopoietic stem cell transplant

S Hingorani - Pediatric Nephrology, 2008 - Springer
liver transplant. However, the long-term affects of preexisting renal disease on developing
CKD after orthotopic liver … In contrast, in adult liver transplant patients who develop acute renal

[HTML][HTML] … derived from human liver stem cells attenuate chronic kidney disease development in an in vivo experimental model of renal ischemia and reperfusion injury

S Bruno, G Chiabotto, M Cedrino, E Ceccotti… - International Journal of …, 2022 - mdpi.com
… of HLSC-EVs to interfere with the development of renal fibrosis, we induced 30 min-IRI with
… developed chronic kidney disease that was characterized by worsening renal function and …

[HTML][HTML] Use of mesenchymal stem cells to treat liver fibrosis: current situation and future prospects

S Berardis, PD Sattwika, M Najimi… - World journal of …, 2015 - ncbi.nlm.nih.gov
… rationale to propose cell therapy and, in particular, MSCs to treat liver fibrosis, overview of …
Some particularities have been documented as in kidney. Indeed, renal fibrosis progression (…

[HTML][HTML] Mesenchymal stem cell therapy for liver fibrosis

YW Eom, KY Shim, SK Baik - The Korean journal of internal …, 2015 - ncbi.nlm.nih.gov
… activities of MSCs have been reported in various fibrotic animal models in the heart, liver,
kidneys, lungs, peritoneum, pancreas, skin, and rectum [54]. MSCs suppress the …

[HTML][HTML] … Derived from Human Liver Stem Cells Counteract Chronic Kidney Disease Development and Cardiac Dysfunction in Remnant Kidney Murine Model: The …

E Ceccotti, G Chiabotto, M Cedrino, A Gambella… - …, 2024 - ncbi.nlm.nih.gov
Fibrosis is a marker of chronic kidney disease (CKD) and consists of the accumulation of the
… deterioration of kidney function. Human liver stem cells (HLSCs) have anti-fibrotic activity, …

[HTML][HTML] Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy

C Grange, S Tritta, M Tapparo, M Cedrino, C Tetta… - Scientific reports, 2019 - nature.com
… by human liver stem-like cells (HLSCs), on the progression and reversion of … renal fibrosis
that develops during diabetic nephropathy progression was significantly inhibited in stem cell

[HTML][HTML] Mesenchymal stem cells in fibrotic disease

E El Agha, R Kramann, RK Schneider, X Li, W Seeger… - Cell stem cell, 2017 - cell.com
… MSC-like cells in myofibroblast-mediated fibrotic disease in the kidney, lung, heart, liver, skin…
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. …

[HTML][HTML] Stem cells in the treatment of renal fibrosis: a review of preclinical and clinical studies of renal fibrosis pathogenesis

Y Liu, YY Su, Q Yang, T Zhou - Stem Cell Research & Therapy, 2021 - Springer
… signaling pathways) of renal fibrosis, and the effect of stem cell therapy on renal fibrosis as
described in preclinical and clinical studies. We found that stem cells from various sources …