High serum matrix metalloproteinase-3 and liver stiffness in postoperative biliary atresia

S Honsawek, K Praianantathavorn… - Pediatric surgery …, 2011 - Springer
… Biliary atresia (BA) is a neonatal liver disorder … metalloproteinase-3 (MMP-3) in postoperative
BA patients and the association of MMP-3 with clinical outcome and liver stiffness score. …

Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation

A Dechêne, JP Sowa, RK Gieseler, C Jochum… - …, 2010 - Wiley Online Library
… with ALF according to the Acute Liver Failure Study Group criteria were … liver stiffness (LS)
with FibroScan, standard laboratory parameters, and serum levels of matrix metalloproteinase

Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis

D Lachowski, E Cortes, A Rice, D Pinato… - Scientific reports, 2019 - nature.com
… the liver is associated with specific rigidities, as determined through ultrasound based transient
elastography. Liver stiffness … An illustration of matrix metalloproteinase 2 and 9 and tissue …

Serum matrix metalloproteinase 7 (MMP7) is a biomarker of fibrosis in patients with non-alcoholic fatty liver disease

KM Irvine, S Okano, PJ Patel, LU Horsfall, S Williams… - Scientific reports, 2021 - nature.com
… The use of the non-invasive liver stiffness measurement as the determinant of fibrosis in
this study necessitated selection of a threshold for significant fibrosis. Whilst appropriate …

Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis

PC Georges, JJ Hui, Z Gombos… - … and Liver …, 2007 - journals.physiology.org
… from the same livers was used to quantify fibrosis. We observed that liver stiffness increased
… We suggest that increased liver stiffness may play an important role in initiating the early …

Molecular cues guiding matrix stiffness in liver fibrosis

T Saneyasu, R Akhtar, T Sakai - BioMed research international, 2016 - Wiley Online Library
… the mechanisms of how ECM stiffness is regulated during the development of liver fibrosis
and the molecules involved in ECM stiffness as a potential therapeutic target for liver fibrosis. …

Concentration of serum matrix metalloproteinase-3 in patients with primary biliary cholangitis

A Bauer, A Habior - Frontiers in Immunology, 2022 - frontiersin.org
… (MMPs) are involved in many distinct processes in the liver. Matrix metalloproteinase-3 (MMP-3) …
that a high serum concentration of MMP-3 can be related to the degree of liver fibrosis. …

Noninvasive assessment of liver fibrosis: current and future clinical and molecular perspectives

R Masuzaki, T Kanda, R Sasaki, N Matsumoto… - International Journal of …, 2020 - mdpi.com
… of shear waves to estimate liver stiffness. There are ultrasound (… 3 inhibits a disintegrin and
metalloproteinase 17 (ADAM17) and its essential role in the liver was confirmed in a Timp-3

Matrix metalloproteinases as potential biomarkers and therapeutic targets in liver diseases

E Geervliet, R Bansal - Cells, 2020 - mdpi.com
… , matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs). In a healthy liver,
… However, during liver injury, quiescent HSCs undergo phenotypic transformation into highly …

Elevation of serum galectin-3 and liver stiffness measured by transient elastography in biliary atresia

S Honsawek, V Chongsrisawat… - European Journal of …, 2011 - thieme-connect.com
… -3 in postoperative BA patients and the association between galectin-3, clinical outcome and
liver stiffness … investigate serum galectin-3 concentrations, liver stiffness scores, and clinical …