[HTML][HTML] Down-regulation of lncRNA CASC2 promotes cell proliferation and metastasis of bladder cancer by activation of the Wnt/β-catenin signaling pathway

Z Pei, X Du, Y Song, L Fan, F Li, Y Gao, R Wu, Y Chen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… function of lncRNA CASC2 in bladder cancer are still unclear. In this study, we found that
lncRNA CASC2 was significantly down-regulated in bladder cancer tissues and cell lines by …

[HTML][HTML] Downregulation of lncRNA CASC2 by microRNA-21 increases the proliferation and migration of renal cell carcinoma cells

Y Cao, R Xu, X Xu, Y Zhou… - Molecular medicine …, 2016 - spandidos-publications.com
… Restoration of CASC2 expression via transfection with a pcDNA3… CASC2 vector was able
to inhibit cell proliferation and migration in 786‑O and A498 cells, as compared with in the cells

Low expression of long noncoding RNA CASC2 indicates a poor prognosis and regulates cell proliferation in non-small cell lung cancer

X He, Z Liu, J Su, J Yang, D Yin, L Han, W De, R Guo - Tumor Biology, 2016 - Springer
… Exogenous CASC2 could inhibit the proliferation of NSCLC cells by affecting cell cycles.
Our results suggest that lncRNA CASC2 may represent a novel indicator of poor prognosis and …

[HTML][HTML] Long non-coding RNA CASC2 suppresses the proliferation of gastric cancer cells by regulating the MAPK signaling pathway

P Li, WJ Xue, Y Feng, QS Mao - American journal of translational …, 2016 - ncbi.nlm.nih.gov
… underlying aberrantly expressed lncRNAs in gastric cancer (GC) is still unclear. In this
study, a novel lncRNA CASC2 was chosen to evaluate the effect on GC cell growth and the …

LncRNA CASC2 interacts with miR‐181a to modulate glioma growth and resistance to TMZ through PTEN pathway

Y Liao, L Shen, H Zhao, Q Liu, J Fu… - Journal of cellular …, 2017 - Wiley Online Library
… We transfected SNB19 and U251 cells with CASC2 vectors or siRNA-CASC2 with the …
the cell viability of glioma cells using MTT assay. Results showed that glioma cell viability was …

[HTML][HTML] Upregulation of lncRNA CASC2 suppresses cell proliferation and metastasis of breast cancer via inactivation of the TGF-β signaling pathway

Y Zhang, M Zhu, Y Sun, W Li, Y Wang, W Yu - Oncology research, 2019 - ncbi.nlm.nih.gov
… , lncRNA CASC2 was found to be significantly downregulated in breast cancer tissues and
cell lines … that overexpression of lncRNA CASC2 significantly repressed breast cancer cell

LncRNA CASC2 inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation and migration by regulating the miR-222/ING5 axis

Y Han, Y Liu, C Yang, C Gao, X Guo… - Cellular & molecular …, 2020 - Springer
lncRNAs as potential candidates for therapeutic intervention in PAH. Recently, lncRNA CASC2
has been revealed to suppress proliferation … mechanisms of CASC2 in proliferation and …

[HTML][HTML] The role of long non-coding RNA CASC2 in the carcinogenesis process

S Ghafouri-Fard, S Dashti, M Taheri - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… The lncRNA cancer susceptibility candidate 2 (CASC2) has … the role of this lncRNA in
suppression of cell proliferation and … of CASC2 suppresses tumorigenesis of human cancer cells

Long non-coding RNA CASC2 suppresses pulmonary artery smooth muscle cell proliferation and phenotypic switch in hypoxia-induced pulmonary hypertension

J Gong, Z Chen, Y Chen, H Lv, H Lu, F Yan, L Li… - Respiratory …, 2019 - Springer
cellular proliferation and apoptosis resistance, we were interested to unveil whether lncRNA
CASC2 … -regulation of lncRNA CASC2 was involved in proliferation and phenotype switch of …

LncRNA CASC2 inhibited the viability and induced the apoptosis of hepatocellular carcinoma cells through regulating miR‐24‐3p

JC Fan, F Zeng, YG Le, L Xin - Journal of Cellular Biochemistry, 2018 - Wiley Online Library
CASC2 and miR-24-3p, suggesting the functional relevance between them. Therefore, we
hypothesized that lncRNA CASC2 … evaluated the effect of CASC2 on the tumor growth in vivo. …