Negative regulation of lncRNA GAS5 by miR-21
… Using the lncRNA RT-PCR (reverse transcription-polymerase chain reaction) array … lncRNAs,
we show that miR-21 is capable of suppressing the lncRNA growth arrest-specific 5 (GAS5)…
we show that miR-21 is capable of suppressing the lncRNA growth arrest-specific 5 (GAS5)…
A long non‐coding RNA, GAS5, plays a critical role in the regulation of miR‐21 during osteoarthritis
J Song, C Ahn, CH Chun, EJ Jin - Journal of orthopaedic …, 2014 - Wiley Online Library
… miR-21 as a regulator of GAS5 during OA pathogenesis. The expression level of miR-21 …
the ectopic expression of GAS5 is capable of suppressing miR-21 induction. Consistent with …
the ectopic expression of GAS5 is capable of suppressing miR-21 induction. Consistent with …
LncRNA GAS5 controls cardiac fibroblast activation and fibrosis by targeting miR-21 via PTEN/MMP-2 signaling pathway
H Tao, JG Zhang, RH Qin, C Dai, P Shi, JJ Yang… - Toxicology, 2017 - Elsevier
… In the present study, we found that GAS5 expression was downregulated while miR-21 was
… of GAS5 inhibits the activation of cardiac fibroblasts, in contrast silencing of GAS5 promotes …
… of GAS5 inhibits the activation of cardiac fibroblasts, in contrast silencing of GAS5 promotes …
Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21
L Hu, H Ye, G Huang, F Luo, Y Liu, Y Liu, X Yang… - Tumor Biology, 2016 - Springer
… In the present study, we show that GAS5 expression is downregulated and miR-21 is … that
GAS5 serves as a miR-21 sponge, we found that GAS5-siRNA increases the miR-21 levels in …
GAS5 serves as a miR-21 sponge, we found that GAS5-siRNA increases the miR-21 levels in …
lncRNA GAS5 is upregulated in osteoporosis and downregulates miR-21 to promote apoptosis of osteoclasts
C Cong, J Tian, T Gao, C Zhou, Y Wang… - … interventions in aging, 2020 - Taylor & Francis
… lncRNA GAS5 could only be precipitated by miR-21 probe but it was undetectable in the …
Figure 4B , p < 0.001), indicating that miR-21 directly interacts with lncRNA GAS5 in osteoblasts. …
Figure 4B , p < 0.001), indicating that miR-21 directly interacts with lncRNA GAS5 in osteoblasts. …
LncRNA GAS5 suppresses proliferation, migration, invasion, and epithelial-mesenchymal transition in oral squamous cell carcinoma by regulating the miR-21/PTEN …
B Zeng, Y Li, F Jiang, C Wei, G Chen, W Zhang… - Experimental cell …, 2019 - Elsevier
… miR-21 overexpression reversed the effect of GAS5 in OSCC For more evidence about
the relationship of GAS5 and miR-21, we transfected pcDNA-GAS5 and mimic-miR-21 …
the relationship of GAS5 and miR-21, we transfected pcDNA-GAS5 and mimic-miR-21 …
Downregulated lncRNA GAS5 and upregulated miR-21 lead to epithelial–mesenchymal transition and lung metastasis of osteosarcomas
Y Wang, X Ren, Y Yuan, BS Yuan - Frontiers in Cell and …, 2021 - frontiersin.org
… effects of GAS5 silencing. Therefore, we next explored if miR-21 levels correlate inversely with
those of GAS5 in … Our analysis revealed that miR-21 levels are significantly upregulated in …
those of GAS5 in … Our analysis revealed that miR-21 levels are significantly upregulated in …
lncRNA GAS5 acts as a ceRNA for miR‐21 in suppressing PDGF‐bb‐induced proliferation and migration in vascular smooth muscle cells
K Liu, C Liu, Z Zhang - Journal of Cellular Biochemistry, 2019 - Wiley Online Library
… , and overexpression of GAS5 remarkably attenuated PDGF-bb-… miR-21 was observed to
potentially bind to GAS5, and we also identified that PDCD4 might be a direct target of miR-21 …
potentially bind to GAS5, and we also identified that PDCD4 might be a direct target of miR-21 …
Long noncoding RNA GAS5, which acts as a tumor suppressor via microRNA 21, regulates cisplatin resistance expression in cervical cancer
Q Wen, Y Liu, H Lyu, X Xu, Q Wu, N Liu, Q Yin… - International Journal of …, 2017 - ijgc.bmj.com
… can not only regulate phosphatase and tensin homolog through miR-21 … GAS5 is a direct
target of miR-21 and can predict the clinical staging of cervical cancer. Most importantly, GAS5 …
target of miR-21 and can predict the clinical staging of cervical cancer. Most importantly, GAS5 …
Long non‑coding RNA GAS5 increases the radiosensitivity of A549 cells through interaction with the miR‑21/PTEN/Akt axis
L Chen, P Ren, Y Zhang, B Gong… - Oncology …, 2020 - spandidos-publications.com
… miRNAs that may be targets of lncRNA GAS5 were assessed and it was demonstrated that
only miR-21 was affected by lncRNA GAS5 … between lncRNA GAS5 and miR-21 has been …
only miR-21 was affected by lncRNA GAS5 … between lncRNA GAS5 and miR-21 has been …
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