[HTML][HTML] lncRNA GAS5 reverses EMT and tumor stem cell-mediated gemcitabine resistance and metastasis by targeting miR-221/SOCS3 in pancreatic cancer

B Liu, S Wu, J Ma, S Yan, Z Xiao, L Wan… - … Therapy-Nucleic Acids, 2018 - cell.com
GAS5 in PC gemcitabine resistance and metastasis. The results show that overexpression
of GAS5 … Thus, lncRNA GAS5 functioned as a competing endogenous RNA for miR-221, and …

[HTML][HTML] Long noncoding RNA GAS5 is critical for maintaining stemness and induces chemoresistance in cancer stem‑like cells derived from HCT116

X Zhou, D Xiao - Oncology Letters, 2020 - spandidos-publications.com
cancer cells (20). Furthermore, it has been reported that in cervical cancer, GAS5 may act as
a tumor … In pancreatic cancer, GAS5 reversed EMT and induced gemcitabine sensitivity by …

[HTML][HTML] Long non-coding RNA GAS5 controls human embryonic stem cell self-renewal by maintaining NODAL signalling

C Xu, Y Zhang, Q Wang, Z Xu, J Jiang, Y Gao… - Nature …, 2016 - nature.com
… Here we demonstrate that growth-arrest-specific transcript 5 (GAS5), a known tumour
function of GAS5 is stem cell specific, our findings also indicate that the functions of lncRNAs may …

[HTML][HTML] Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells

J Tu, G Tian, HH Cheung, W Wei, T Lee - Stem cell research & therapy, 2018 - Springer
… We observed that the tumor size in Gas5 KD mESC-formed teratomas … lncRNAs have been
previously linked to stem cell pluripotency [6], we report for the first time that the lncRNA Gas5

[HTML][HTML] Long noncoding RNA GAS5 in human cancer

X Yang, Z Xie, X Lei, R Gan - Oncology letters, 2020 - spandidos-publications.com
… therapeutic roles of GAS5 in different tumors were reviewed, with a summary of the potential
clinical application of the lncRNA, which may help identify novel study directions for GAS5. …

Novel tumor suppressor lncRNA growth arrest-specific 5 (GAS5) in human cancer

Y Yu, SS Hann - OncoTargets and therapy, 2019 - Taylor & Francis
… is lncRNA GAS5, which is mainly identified as a tumor suppressor in several cancers. GAS5
… Citation99 GAS5 suppressed glioma stem cells (GSCs) malignancy through a miR196a-5p/…

[HTML][HTML] LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p …

TT Lu, X Tao, HL Li, L Gai, H Huang… - Asian journal of …, 2022 - journals.lww.com
… shown that lncRNAs play vital roles in the progression of cancer regulation and chemotherapy
resistance. In this study, we found that the lncRNA GAS5 acts as a tumor suppressor and …

Bone Marrow Mesenchymal Stem Cells with Long Non-Coding RNA-Growth Arrest Specific 5 (LncRNA-GAS5) Modification Impede the Migration and Invasion …

Z Huang, Y Lin, M Zhao, S Li, Y Wen… - … of Biomaterials and …, 2023 - ingentaconnect.com
… -GAS5 overexpression. … EMT involves in the inhibitory effect of LncRNAGAS5-modified BMSCs
on PTC cells, … Qiu, LncRNA GAS5 expression in non-small cell lung cancer tissues and its …

[HTML][HTML] Molecular and cellular mechanisms of action of tumour suppressor GAS5 LncRNA

MR Pickard, GT Williams - Genes, 2015 - mdpi.com
… /glucocorticoid receptor interaction, including the identity of both the bases within the stem-loop
HRE mimic (HREM) sequence of GAS5 lncRNA and the amino acids within the DNA …

LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo

L Chen, H Yang, Y Xiao, X Tang, Y Li… - OncoTargets and …, 2016 - Taylor & Francis
… the expression of lncRNA GAS5 among melanoma cells … GAS5 in SK-Mel-110 cell line in
which GAS5 expression is the least, and knocking down GAS5 in A375 cell line where GAS5