Long noncoding RNA MALAT1: insights into its biogenesis and implications in human disease

Y Wu, C Huang, X Meng, J Li - Current pharmaceutical design, 2015 - ingentaconnect.com
… Furthermore, a growing body of fundamental researches had revealed the underlying
mechanisms for the functions of MALAT1 in CRC. For instance, tumor suppressor gene SFPQ …

The role and mechanism of MALAT1 long non-coding RNA in the diagnosis and treatment of head and neck squamous cell carcinoma

D Ye, Y Deng, Z Shen - OncoTargets and therapy, 2021 - Taylor & Francis
… the role of MALAT1 in the diagnosis and treatment of HNSCC and its regulatory mechanism.
lncRNA MALAT1 renders LSCC less sensitive to chemotherapeutics by boosting tumor cell …

The effects of lncRNA MALAT1 on proliferation, invasion and migration in colorectal cancer through regulating SOX9

Y Xu, X Zhang, X Hu, W Zhou, P Zhang, J Zhang… - Molecular …, 2018 - Springer
… For the study, we determine the potential biomarkers and uncover the regulatory
mechanisms of lncRNA MALAT1 / miR-145 / SOX9 axis on the abilities of cell growth and cell …

LncRNA MALAT1 and Ischemic Stroke: Pathogenesis and Opportunities

SE Khoshnam, A Moalemnia, O Anbiyaee… - Molecular …, 2023 - Springer
… In this review, we provide a comprehensive overview of MALAT1 as a lncRNA in the context
… in pathogenic mechanisms following IS. Understanding the role of MALAT1 in IS may …

MALAT1 lncRNA and Parkinson's Disease: The role in the Pathophysiology and Significance for Diagnostic and Therapeutic Approaches

M Abrishamdar, MS Jalali, M Rashno - Molecular neurobiology, 2022 - Springer
… This narrative review discussed all aspects of MALAT1-associated mechanisms involved in
the PD pathogenesis, ie, perturbed α-synuclein homeostasis, apoptosis and autophagy, and …

Expression and function of lncRNA MALAT-1 in the embryonic development of zebrafish

M Wu, S Zhang, X Chen, H Xu, X Li - Gene, 2019 - Elsevier
… the elucidation of the function and regulation mechanism of lncRNA is of great significance
… , it has been found that lncRNA plays a very important role in the regulation of animal …

Long non-coding RNA MALAT1: A key player in liver diseases

J Lu, J Guo, J Liu, X Mao, K Xu - Frontiers in medicine, 2022 - frontiersin.org
MALAT1 plays a regulatory role in liver diseases, including hepatic fibrosis, … the function
roles of MALAT1 in liver disorders. Probing the regulatory mechanism and cross talk of MALAT1

LncRNA MALAT1 promotes tumorigenesis and immune escape of diffuse large B cell lymphoma by sponging miR-195

QM Wang, GY Lian, Y Song, YF Huang, Y Gong - Life sciences, 2019 - Elsevier
… In this research, we focused on uncovering the upstream mechanisms of PD-L1 … lncRNA
MALAT1, miR-195 and PD-L1 in DLBCL. We elucidated that the long non-coding RNA MALAT1

LncRNA MALAT1-related signaling pathways in osteosarcoma

M Farzaneh, S Najafi, O Anbiyaee, S Azizidoost… - Clinical and …, 2023 - Springer
… , MALAT1 might be a suitable approach for OS diagnosis and treatment. In this review, we will
summarize the role of lncRNA MALAT1mechanism for oncogenic roles of MALAT1 in OS. …

MALAT1 long non-coding RNA in cancer

R Yoshimoto, A Mayeda, M Yoshida… - … regulatory mechanisms, 2016 - Elsevier
… of MALAT1 in many aspects of cancer pathogenesis [13]. This review focuses on the
characteristics and functions of MALAT1, … Here we discuss the functions of these MALAT1-binding …