LncRNA PCAT1 activates AKT and NF-κB signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKKα complex
Z Shang, J Yu, L Sun, J Tian, S Zhu… - Nucleic acids …, 2019 - academic.oup.com
… NF-κB signaling involves a key regulatory protein complex containing PHLPP, FKBP51 and
IKKα. Here, we report a critical role of lncRNA PCAT1 in … that the lncRNA-PCAT1 perturbs the …
IKKα. Here, we report a critical role of lncRNA PCAT1 in … that the lncRNA-PCAT1 perturbs the …
PCAT1: An oncogenic lncRNA in diverse cancers and a putative therapeutic target
… This lncRNA has a number of putative functional … PCAT1 thus altering the risk of human
cancers. Based on aberrant expression of PCAT1 in malignancies of diverse origins, this lncRNA …
cancers. Based on aberrant expression of PCAT1 in malignancies of diverse origins, this lncRNA …
Long non-coding RNA PCAT-1 regulates apoptosis of chondrocytes in osteoarthritis by sponging miR-27b-3p
L Zhou, M Gu, X Ma, L Wen, B Zhang, Y Lin… - Journal of Bone and …, 2021 - Springer
… Based on the comparisons and analysis, we could conclude that lncRNA PCAT-1 regulated
the apoptosis of chondrocytes through sponging miR-27b-3p in OA. PCAT-1 has potential …
the apoptosis of chondrocytes through sponging miR-27b-3p in OA. PCAT-1 has potential …
[PDF][PDF] LncRNA PCAT1 enhances cell proliferation, migration and invasion by miR-508-3p/NFIB axis in diffuse large B-cell lymphoma.
M Tian, Y Li, W Zheng, XL ZHANG… - European Review for …, 2021 - europeanreview.org
… human tumors, the role of PCAT1 in DLBCL is still scarce. … of PCAT1 in DLBCL, and indicated
the effect of PCAT1 on the development of DLBCL. Simultaneously, we found that PCAT1 …
the effect of PCAT1 on the development of DLBCL. Simultaneously, we found that PCAT1 …
PCAT‐1 promotes cell growth by sponging miR‐129 via MAP3K7/NF‐κB pathway in multiple myeloma
X Shen, S Kong, Q Yang, Q Yin, H Cong… - Journal of Cellular …, 2020 - Wiley Online Library
… Notably, we showed that MAP3K7 along with NF-κB signal could affect cell division and
apoptosis under the regulation of miR-129. Additionally, we identified that lncRNA PCAT-1 could …
apoptosis under the regulation of miR-129. Additionally, we identified that lncRNA PCAT-1 could …
LncRNA PCAT1 interacts with DKC1 to regulate proliferation, invasion and apoptosis in NSCLC cells via the VEGF/AKT/Bcl2/Caspase9 pathway
SY Liu, ZY Zhao, Z Qiao, SM Li… - Cell …, 2021 - journals.sagepub.com
… In this research, we evaluated the expression of lncRNA PCAT1 in 20 paired human NSCLC
tumor tissues and adjacent tissues and found that the PCAT1 was significantly upregulated …
tumor tissues and adjacent tissues and found that the PCAT1 was significantly upregulated …
[HTML][HTML] Exosomal lncRNA PCAT-1 promotes Kras-associated chemoresistance via immunosuppressive miR-182/miR-217 signaling and p27/CDK6 regulation
K Domvri, S Petanidis, D Anestakis, K Porpodis, C Bai… - Oncotarget, 2020 - ncbi.nlm.nih.gov
… that long noncoding RNAs (lncRNAs) present in the … of lncRNA PCAT-1 in chemoresistant
immunosuppression and its involvement in tumor stroma remodeling. Findings reveal PCAT-1 …
immunosuppression and its involvement in tumor stroma remodeling. Findings reveal PCAT-1 …
Exosomal lncRNA PCAT1 Promotes Tumor Circulating Cell‐Mediated Colorectal Cancer Liver Metastasis by Regulating the Activity of the miR‐329‐3p/Netrin‐1 …
X Fang, Y Xu, K Li, P Liu, H Zhang… - Journal of …, 2022 - Wiley Online Library
… This study found that lncRNA PCAT1 was abnormally highly expressed in exosomes of
colorectal cancer cells and determined that PCAT1 can promote the occurrence of EMT in …
colorectal cancer cells and determined that PCAT1 can promote the occurrence of EMT in …
[HTML][HTML] PCAT-1: a novel oncogenic long non-coding RNA in human cancers
T Xiong, J Li, F Chen, F Zhang - International Journal of Biological …, 2019 - ncbi.nlm.nih.gov
… lncRNAs act as multiple roles in biological processes of diseases, … (PCAT-1) is an oncogenic
lncRNA that identified by RNA-Sequence in prostate cancer. High expression of PCAT-1 is …
lncRNA that identified by RNA-Sequence in prostate cancer. High expression of PCAT-1 is …
LncRNA PCAT1 activates SOX2 and suppresses radioimmune responses via regulating cGAS/STING signalling in non‐small cell lung cancer
Y Gao, N Zhang, Z Zeng, Q Wu, X Jiang… - Clinical and …, 2022 - Wiley Online Library
… Using various cohorts of database of NSCLC, we identified and validated PCAT1 as an
immunosuppressive and invasion-related lncRNA in NSCLC. Increased PCAT1 was negatively …
immunosuppressive and invasion-related lncRNA in NSCLC. Increased PCAT1 was negatively …