Inflection points in sepsis biology: from local defense to systemic organ injury
EJ Seeley, MA Matthay… - American Journal of …, 2012 - journals.physiology.org
… combating local infections yet can induce organ injury during systemic infection. … locally
beneficial host defense mechanisms can become detrimental when activated systemically. Local …
beneficial host defense mechanisms can become detrimental when activated systemically. Local …
[PDF][PDF] From Local Defense to Remote Organ Injury
H Akbarshahi - Lund University, Faculty of Medicine Doctoral …, 2013 - Citeseer
… Experimental models of acute pancreatitis and remote organ injury … of acute pancreatitis
and remote organ injury. By using these … and remote organ injury has been identified [109]. …
and remote organ injury. By using these … and remote organ injury has been identified [109]. …
Normal responses to injury prevent systemic inflammation and can be immunosuppressive
RS Munford, J Pugin - American journal of respiratory and critical …, 2001 - atsjournals.org
… Natural antibodies, the alternative complement pathway, and local inflammation are … local
defenses by preventing both microbial dissemination and self-inflicted injury to distant organs…
defenses by preventing both microbial dissemination and self-inflicted injury to distant organs…
Mechanisms of organ injury and repair by macrophages
KM Vannella, TA Wynn - Annual review of physiology, 2017 - annualreviews.org
… local hypoxia that develops following injury (8–12). They also produce soluble mediators such
as TGF-β1 that stimulate local … defense in the lung, they can also contribute to tissue injury…
as TGF-β1 that stimulate local … defense in the lung, they can also contribute to tissue injury…
Multiple systems organ failure: failure of host defense homeostasis
MR Pinsky, GM Matuschak - Critical care clinics, 1989 - criticalcare.theclinics.com
… without other extrapulmonic organ injury is a localized … generalized endothelial injury in
multiple organs. Accordingly, … Consequently, increased local tissue oxygen demand may …
multiple organs. Accordingly, … Consequently, increased local tissue oxygen demand may …
[HTML][HTML] CD11c+ cells are required to prevent progression from local acute lung injury to multiple organ failure and death
JE Milam, JR Erb-Downward, GH Chen… - The American journal of …, 2010 - Elsevier
… of local lung tissue revealed no differences in acute lung injury … severe damage and necrosis
to multiple organs (liver, spleen, … in protecting the organs from systemic injury caused by a …
to multiple organs (liver, spleen, … in protecting the organs from systemic injury caused by a …
Novel synthetic, host-defense peptide protects against organ injury/dysfunction in a rat model of severe hemorrhagic shock
N Yamada, LB Martin, E Zechendorf… - Annals of …, 2018 - journals.lww.com
… HS and quantification of organ injury and dysfunction were … , which makes these organs
less resistant to organ injury. In … Akt-survival pathway reduces organ injury in many conditions …
less resistant to organ injury. In … Akt-survival pathway reduces organ injury in many conditions …
Multiple organ injuries and failures caused by shock and reperfusion after gunshot wounds
X Fu, H Tian, D Wang, Y Yao, Y Wang… - Journal of Trauma and …, 1996 - journals.lww.com
… the changes of multiple system organ failure (MSOF) and gut … group developed multiple
system organ injuries or failures … The pathological results support the gut barrier function injury…
system organ injuries or failures … The pathological results support the gut barrier function injury…
Systemic inflammation and remote organ injury following trauma require HMGB1
RM Levy, KP Mollen, JM Prince… - American Journal …, 2007 - journals.physiology.org
… end-organ injury after peripheral tissue injury, we … injury stimulates a local inflammatory
response but also sets in motion a systemic inflammatory cascade leading to remote organ injury …
response but also sets in motion a systemic inflammatory cascade leading to remote organ injury …
Complement activation and organ damage after trauma—differential immune response based on surgical treatment strategy
I Lackner, B Weber, M Baur, G Fois, F Gebhard… - Frontiers in …, 2020 - frontiersin.org
… to investigate the complement activation in multiply injured pigs as well as its … injured pigs
showed complement activation in serum within 6 h after trauma, we next investigated the local …
showed complement activation in serum within 6 h after trauma, we next investigated the local …
相关搜索
- host defense organ injury dysfunction
- remote organ injury
- local defense systemic organ injury
- multiple organ injury
- systems organ failure host defense homeostasis
- post-injury multiple organ failure
- inflection points systemic organ injury
- organ injury endothelial barrier dysfunction
- severe hemorrhagic shock organ injury dysfunction
- organ injury experimental study in rats
- rat model organ injury dysfunction
- organ injury systemic inflammation
- blunt injury multiple organ failure
- lung injury multiple organ failure