Function and information content of DNA methylation

D Schübeler - Nature, 2015 - nature.com
… assign a function to the local presence of DNA methylation at particular genes has remained
… function of DNA methylation in mammals, and discusses the utility of DNA methylation as a …

DNA methylation in human epigenomes depends on local topology of CpG sites

C Lövkvist, IB Dodd, K Sneppen… - Nucleic acids …, 2016 - academic.oup.com
… enzymes that can act on CpGs over an extended local region, while … methylation status,
would allow systematic determination of the general geometric rules for DNA methylation

[HTML][HTML] DNA methylation in Arabidopsis has a genetic basis and shows evidence of local adaptation

MJ Dubin, P Zhang, D Meng, MS Remigereau… - elife, 2015 - elifesciences.org
… the levels of DNA methylation, and they provide the first direct link between DNA methylation
and adaption to the environment. Future studies should reveal how DNA methylation is …

[HTML][HTML] Daily variation in global and local DNA methylation in mouse livers

L Xia, S Ma, Y Zhang, T Wang, M Zhou, Z Wang… - PloS one, 2015 - journals.plos.org
… Previous studies have reported that DNA methylation in human blood shows 24-h variation
[… the DNA methylation state [31]. In this study, we found that global DNA methylation level in …

New concepts in DNA methylation

A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
DNA methylation at each site is determined by the local … Second, we present a modified
stochastic DNA methylation … de novo and the maintenance methylation process at CpG and non-…

DNA methylation has a local effect on transcription and histone acetylation

RA Irvine, IG Lin, CL Hsieh - Molecular and cellular biology, 2002 - Taylor & Francis
… Our findings with stable episomes in human cells support the view that DNA methylation
affects transcription locally and that the impact on transcription is negligible when methylation is …

Genome-wide evidence for local DNA methylation spreading from small RNA-targeted sequences in Arabidopsis

I Ahmed, A Sarazin, C Bowler, V Colot… - Nucleic acids …, 2011 - academic.oup.com
DNA methylation (RdDM) machinery. We provide evidence that these TE sequences acquire
DNA methylation … we propose that spreading of DNA methylation through promoter regions …

[HTML][HTML] Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles

A Martin-Trujillo, N Patel, F Richter, B Jadhav… - PLoS …, 2020 - journals.plos.org
DNA methylation profiles locally [15,16], we hypothesized that the disruption of TFBSs by rare
SNVs can modify local DNA methylation … we combined blood DNA methylation profiles and …

Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation

A Martin-Trujillo, P Garg, N Patel, B Jadhav… - Genome …, 2023 - genome.cshlp.org
… act as independent regulators of local DNA methylation in the … ) and genome-wide DNA
methylation levels derived from whole… major genetic modulator of local DNA methylation profiles. …

The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood

SM Langevin, EA Houseman, BC Christensen… - Epigenetics, 2011 - Taylor & Francis
… of the potential for local sequence features and genomic context to influence the methylation
state of CpGs will enhance our comprehension of how DNA methylation is regulated under …