[HTML][HTML] Head and neck cancer exosomes drive microRNA-mediated reprogramming of local neurons

PJ Hunt, M Amit - Extracellular vesicles and circulating nucleic …, 2020 - ncbi.nlm.nih.gov
… nearby autonomic neurons arise through direct signaling between tumors and local neurons.
… The neurons innervating p53-deficient OCSCC tumors were predominantly adrenergic and …

Advances in head and neck cancer pain

Y Ye, DD Jensen, CT Viet, HL Pan… - Journal of dental …, 2022 - journals.sagepub.com
neuronal reprogramming and neurogenesis on cancerneuronal hypersensitivity, nerve
injury, and neuropathic pain, in addition to direct neuronal activation and sensitization by cancer

Tumor Neurobiology in the Pathogenesis and Therapy of Head and Neck Cancer

S Liang, J Hess - Cells, 2024 - mdpi.com
… The study showed an increase in dorsal root ganglion neurons in prostate cancer patients, …
Local denervation via surgical or pharmacological intervention is another potential strategy …

Neural landscape is associated with functional outcomes in irradiated patients with oropharyngeal squamous cell carcinoma

S Islam, FO Gleber-Netto, CF Mulcahy… - Science Translational …, 2024 - science.org
… further analyze the neuronal populations associated with … in patients with advanced head
and neck cancers (25), we … that these symptoms were driven by local sensory effects. High-…

HPV+ head and neck cancer–derived small extracellular vesicles communicate with TRPV1+ neurons to mediate cancer pain

KE Inyang, CM Evans, M Heussner, M Petroff… - Pain, 2024 - journals.lww.com
… and neck squamous cell carcinoma–derived sEVs alter TRPV1+ neurons by promoting nascent
translation to mediate cancer … Once released, sEVs act on local or distant target cells and …

[HTML][HTML] Radiation-induced neuropathies in head and neck cancer: prevention and treatment modalities

P Azzam, M Mroueh, M Francis… - …, 2020 - ncbi.nlm.nih.gov
neuronal substructures. Neuropathic sequelae following irradiation in the head and neck area
… modalities to palliate common radiation-induced neuropathies in head and neck cancers. …

The role of postoperative radiotherapy for large nerve perineural spread of cancer of the head and neck

P Gorayski, M Foote, S Porceddu… - Journal of Neurological …, 2016 - thieme-connect.com
… potential space surrounding neuronal axons and occurs in 2 to 6% of cutaneous head
and … The predominant pattern of failure was local in-field (20%), followed by local out-of-field/…

Types and causes of pain in cancer of the head and neck

CJ Vecht, AM Hoff, PJ Kansen, MF De Boer… - Cancer, 1992 - Wiley Online Library
… tumor or local benign inflammation, or the sequels of neck … Stimulation of these nociceptive
neurons leads to pain in the … that pain in head and neck cancer is often located close to the …

Research progress on mechanism and imaging of temporal lobe injury induced by radiotherapy for head and neck cancer

Z Zheng, B Wang, Q Zhao, Y Zhang, J Wei, L Meng… - European …, 2022 - Springer
… the cytomechanical properties of cortical neurons [27]. Wang et … neurons or glial cells and
are sensitive to radiation [29]. Autophagy plays an important role in the execution of neuronal

Regulation of carcinogenesis by sensory neurons and neuromediators

N Erin, GV Shurin, JH Baraldi, MR Shurin - Cancers, 2022 - mdpi.com
… Hence, in this review, we mainly focus on local and systemic … perineural invasion (PNI) by
cancer of the space surrounding a … cancers, head and neck cancers, prostate cancers, skin …