Projections from the periaqueductal gray to the rostromedial pericoerulear region and nucleus locus coeruleus: anatomic and physiologic studies

M Ennis, M Behbehani, MT Shipley… - Journal of …, 1991 - Wiley Online Library
… Previous studies showed that the nucleus locus coeruleus (LC) receives two major afferent
inputs … Recent reports suggested that the midbrain periaqueductal gray (PAG) projects to the …

Opposite modulation of opiate withdrawal behaviors on microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray

LJ Punch, DW Self, EJ Nestler… - Journal of …, 1997 - Soc Neuroscience
… Chronic opiate administration upregulates the cAMP pathway in the locus coeruleus (LC). …
Infusions into amygdala or periaqueductal gray (PAG) were studied for comparison. In one …

Periaqueductal gray: an interface for behavioral control

EE Benarroch - Neurology, 2012 - AAN Enterprises
… The PAG projects densely to the nucleus cuneiformis; locus ceruleus; Barrington nucleus
(pontine micturition center); motor nuclei of the pontomedullary reticular formation; …

Collateralized projections from neurons in the rostral medulla to the nucleus locus coeruleus, the nucleus of the solitary tract and the periaqueductal gray

EJ Van Bockstaele, G Aston-Jones - Neuroscience, 1992 - Elsevier
locus coeruleus and the lateral periaqueductal gray, but separate populations of neurons
project to the locus coeruleus and the lateral periaqueductal gray … link the locus coeruleus and …

Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation

ST Lubejko, G Livrizzi, SA Buczynski, J Patel… - Science …, 2024 - science.org
… Here, we establish that noradrenergic neurons of the locus coeruleus (LC) are essential
for … driven by excitatory output from the ventrolateral periaqueductal gray (vlPAG) to the LC. …

Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus

R Bodnar, D Paul, GW Pasternak - Brain research, 1991 - Elsevier
gray and the locus coeruleus. However, microinjection of EKC into either the periaqueductal
gray or locus coeruleus … both the periaqueductal gray (10 #g) and the locus coeruleus (10 gg…

Protein kinases in the locus coeruleus and periaqueductal gray matter are involved in the expression of opiate withdrawal

R Maldonado, O Valverde, C Garbay… - … archives of pharmacology, 1995 - Springer
… in the locus coeruleus and the periaqueductal gray matter. … and the locus coeruleus or the
periaqueductal gray matter. … per side) into the locus coeruleus induced a strong attenuation of …

The ascending input to the midbrain periaqueductal gray of the primate

PW Mantyh - Journal of Comparative Neurology, 1982 - Wiley Online Library
… colliculus, periaqueductal gray, lateral parabrachial, locus coeruleus, … The locus coeruleus
(LC) is an adrenergic cell group (… The labeled locus coeruleus cells present in this study are …

Expression of GAD2 in excitatory neurons projecting from the ventrolateral periaqueductal gray to the locus coeruleus

EK Harding, Z Zhang, J Canet-Pons, S Stokes-Heck… - iScience, 2024 - cell.com
… The ventrolateral periaqueductal gray (vlPAG) functionally projects to diverse brain regions,
including the locus coeruleus (LC). Excitatory projections from the vlPAG to the LC are well …

Investigating the role of the locus coeruleus in Periaqueductal Gray-mediated Antinociception

S Lubejko, G Livrizzi, MR Banghart - The Journal of Pain, 2022 - jpain.org
… Activity in the ventrolateral periaqueductal gray (vlPAG) has been shown to be …
Although the locus coeruleus (LC) has been shown to modulate nociception, its role in and …