… long-term safety results from this study are consistent with the known safety profile of
pirfenidone, with no new safety … These findings support the clinical use of pirfenidone in patients …

… Our results show that long-term treatment with pirfenidone (median duration, 2.6 years)
was safe and generally well tolerated. Gastrointestinal and skin-related events were the most …

… long-term safety in patients who were prescribed pirfenidone. The study was conducted
in accordance with the pre-defined protocol and all applicable laws and regulations (including …

… have concluded that the longer term safety profile of pirfenidone appears to be consistent
with those seen in the clinical trials. No new or unexpected safety signals have, as yet, …

… enrolled (20.9%) had respiratory failure and were under long term oxygen treatment. Pulmonary
hypertension was present (as estimated by right ventricle systolic pressure (RVSP) > 35 …

… Long-term effects of pirfenidone have been poorly understood to date. This study investigated
the clinical efficacy and safety of long-term pirfenidone use … treated with pirfenidone. This …

… in the above cited studies, with similar change scores even at 3 years among patients who
continued treatment in the long term. Furthermore, mean functional parameters had slightly …

… of pirfenidone treatment, the potential adverse events (AEs) associated with pirfenidone …
This review highlights the well-known and established safety profile of pirfenidone based on …

… Previous pirfenidone trials have only involved patients with mild-to-moderate idiopathic …
The aim of this study was to investigate the safety and efficacy of pirfenidone in patients with …

… of IPF patients (n=1009) who were newly prescribed pirfenidone and followed for 2 years
thereafter… The aim of the study to evaluate long-term safety of pirfenidone. Median pirfenidone …