… Multiple sclerosis (MS) is a chronic, inflammatory demyelinating disease of the central …
progressive multiple sclerosis (PPMS) affects 10–15% of all MS patients and is the least studied …

… In this work, we aimed to confirm the current knowledge of the optic nerve assessment in
patients with CIS by conducting a multicenter, longitudinal, prospective study and using all the …

Background: The risk factors for conversion from relapsing-remitting to secondary progressive
multiple sclerosis remain highly contested. Objective: The aim of this study was to …

… first longitudinal multicenter study analyzing the prevalence and potential biopsychosocial
determinants of pain of any type (UP) and neuropathic pain (NP) in a large cohort of patients …

… In a longitudinal, multicenter sample of 3,565 magnetic resonance imaging (MRI) scans,
in 1,204 patients with MS and clinically isolated syndrome (CIS) and 150 healthy controls (mean …

… This highlights the need for larger, multicenter studies with longer durations of follow-up to
fully interrogate the longitudinal effects of vascular risk factors on new lesion development in …

… 4 of 21 patients (19 percent… multiple sclerosis was 3.25 (range, 0 to 10); 31 percent had an
EDSS score of 6 or more (including three patients whose deaths were due to multiple sclerosis…

… which mainly characterize RRMS patients. To test these, we measured CTh from 3D T1-weighted
scans of a multicentre cohort of healthy controls (HC) and patients with RRMS and …

… The study design was possible because of the willingness of patients at one of the sites
of a multicenter trial to enroll in a long-term follow-up study. …

… Introduction: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative
… longitudinal multi-centre cohort study, which focuses on deeply phenotyping patients with …