… in the Look AHEAD (Action for Health in Diabetes) study and identifies factors associated with
long-term success. A … These results provide critical evidence that a comprehensive lifestyle …

… appears to be slowing over time. The weight losses in the Look AHEAD trial are impressive
in … 2 DM, 25 the Look AHEAD trial provides unique data on long-term changes in fitness. The …

The Look AHEAD (Action for Health in Diabetes) study is a multicenter, randomized
controlled trial designed to determine whether intentional weight loss reduces cardiovascular …

… longer term success with behavioral interventions (12,13,14,15). A separate analysis of Look
AHEAD … achieving an initial 7% weight loss strongly predicted longer term weight loss (16). …

… In summary, these secondary findings, combined with the primary Look AHEAD study results,
9 lead to several conclusions about the effect of intentional weight loss. First, as reported in …

… To examine the sensitivity of the results to this definition, we did secondary analyses of
treatment effects on other renal outcomes: very-high-risk CKD confirmed at the next examination, …

… Follow-up of Look AHEAD participants is ongoing and is … criteria were set by the Look
AHEAD study group based on 1-… This report documents the success of Look AHEAD in meeting …

… The Look AHEAD Study found no significant reduction in cardiovascular disease (CVD) …
We examined whether CVD incidence in Look AHEAD varied by weight or fitness change. …

… of producing long-term changes in these risk factors. Therefore, the Look AHEAD lifestyle
intervention incorporates strategies expected to maximize long-term weight loss success, …

… of retention, the success of the Look AHEAD intervention in producing long-term changes in
… or impairment were obtained at enrollment into the Look AHEAD trial; however, risk factors …