… The goal of this paper is to discuss the history of Look AHEAD, … The impetus for Look AHEAD
came from observational studies … Figure 1 shows the timeline for the Look AHEAD study. …

… Look AHEAD was a randomized trial of ILI compared with diabetes support and education
(… individuals with overweight/obesity and type 2 diabetes (12). The Look AHEAD intervention …

… Look AHEAD assessed the effects of intentional weight loss on cardiovascular morbidity and
mortality in 5,145 overweight/obese adults with type 2 diabetes, randomly assigned to ILI or …

… compared with overweight or moderate obesity (ie, BMI <40 kg/m 2 ) (3). For these reasons,
it is critical that effective treatment options for this population be identified and implemented. …

… The Look AHEAD trial was a randomized controlled trial comparing an intensive lifestyle
intervention (ILI) to diabetes support and education (DSE) in overweight and obese type 2 …

… Look AHEAD (Action for Health in Diabetes) study and identifies factors associated with
long-term success. A total of 5,145 overweight/obese … 5%) in overweight/obese participants with …

… overweight and obese individuals with type 2 diabetes because of its large and demographically
diverse patient population. Look AHEAD … examined whether Look AHEAD participants …

… In the present study, we excluded Look AHEAD participants with any HF at baseline and
therefore adjudicated incident HF. As part of a Look AHEAD HF ancillary study, follow-up was …

… In Look AHEAD , overweight or obese individuals with type 2 diabetes were randomly … Key
inclusion criteria were age 45–76 years, overweight or obese (BMI ≥25 kg/m 2 in those not …

… for obesity and its manifold health effects. Surging media attention to obesity and overweight
… the first to live shorter lives than their parents—and obesity is to blame”; Belluck 2005, p. A1; …