Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan and captopril

JC Balt, MJ Mathy, M Pfaffendorf… - Journal of …, 2001 - journals.lww.com
… male, normotensive pithed rat model, we studied the effect of losartan (1, 3, 10 and 30 mg/kg),
irbesartan (3, 10, 30 and 60 mg/kg), telmisartan (0.3, 1, 3 and 10 mg/kg) and captopril (1.5, …

Losartan and captopril follow different mechanisms to decrease pressor responses in the pithed rat

H Yokoyama, S Minatoguchi, M Koshiji… - Clinical and …, 1997 - Wiley Online Library
… presence of losartan and captopril in the pithed rat, we compared the effects of losartan and
captopril on the release of NA from sympathetic nerve endings in the pithed rat. Furthermore, …

Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7)

I Kucharewicz, R Pawlak, T Matys, D Pawlak… - …, 2002 - Am Heart Assoc
… Also, in vivo Ang-(1-7) decreases blood pressure in spontaneously hypertensive rats, pithed
rats… As for captopril, we have shown recently that a thiol group of this drug is important for its …

The effects of losartan and captopril on vasopressor actions of cirazoline in the absence and presence of SZL-49 and nifedipine

R Tabrizchi, SM Lupichuk - Journal of cardiovascular …, 1995 - journals.lww.com
Losartan (5.0 mg/kg) and captopril (3.0 mg/kg… pithed rats. Continuous infusion with vasopressin
vvas used to restore the blood pressure of pithed rats pretreated with losartan or captopril

… of the AT1 antagonist HR 720 in comparison to losartan on stimulated sympathetic outflow, blood pressure, and heart rate in pithed spontaneously hypertensive rats

W Häuser, A Dendorfer, T Nguyen… - Kidney and Blood …, 1998 - karger.com
… AT1A and AT1B, exist in the rat [11], but they cannot be discriminated by losartan [11, 37]. To
… In conclusion, these results show that the effects of Ang II in the pithed rat, ie, the increases …

Prevention of angiotensin II induced myocyte necrosis and coronary vascular damage by lisinopril and losartan in the rat

A Kabour, JR Henegar, VR Devineni… - Cardiovascular …, 1995 - academic.oup.com
… be preventable with antihypertensive doses of captopril that were markedly greater than the
… vascular bed,16 and the vasculature of pithed rats.” However, Bhan et al6 concluded that …

A facilitatory effect of anti‐angiotensin drugs on vagal bradycardia in the pithed rat and guinea‐pig

M Rechtman, H Majewski - British journal of pharmacology, 1993 - Wiley Online Library
… inhibitor, captopril, had a marked hypotensive action in pithed rats which was not seen in …
receptor blockade produced by losartan, which contrasts with the captopril situation where the …

Involvement of nitric oxide, but not prostaglandins, in the vascular sympathoinhibitory effects of losartan in the pithed spontaneously hypertensive rat

C Richer, V Domergue, MP Vincent… - British journal of …, 1996 - Wiley Online Library
… by losartan versus the vascular responses elicited by spinal cord electrical stimulation (SCS)
in … Captopril interferes with neurogenic vasoconstriction in the pithed rat by angiotensin…

[PDF][PDF] Angiotensin II pressor response in the L-NAME-induced hypertensive pithed rat: Role of the AT1 receptor

ES Figueroa-Guillén, P Castro-Moreno… - … West. Pharmacol. Soc, 2009 - researchgate.net
rats a greater maximal effect was observed, indicating that L-NAME promotes Ang II
hypersensitivity. In L-NAME-treated rats, Ang II response was blocked by losartanrats with …

Interaction between lifetime captopril treatment and NaCl-sensitive hypertension in spontaneously hypertensive rats and Wistar–Kyoto rats

Z Fang, W Sripairojthikoon, DA Calhoun… - Journal of …, 1999 - journals.lww.com
… In untreated WKY rats, the high NaCl diet did … captopril-treated WKY rats the high NaCl diet
induced a rapid rise in arterial pressure. In WKY rats, discontinuation of the lifetime captopril