Oxidized lowdensity lipoprotein induces endothelial progenitor cell senescence, leading to cellular dysfunction

T Imanishi, T Hano, T Sawamura… - Clinical and …, 2004 - Wiley Online Library
… marrow-derived endothelial progenitor cells (EPC). We investigated the effect of oxidized
low-density lipoprotein (ox-LDL) on the senescence of EPC, leading to cellular dysfunction. …

Endothelial dysfunction, oxidation of lowdensity lipoprotein, and cardiovascular disease

P Holvoet - Therapeutic apheresis, 1999 - Wiley Online Library
… Hypercholesterolemia induces microvascular dysfunction characterized by loss of …
Endothelial cell dysfunction may be the consequence of increased endocytic activity in cells

[PDF][PDF] Cellular and molecular mechanisms of endothelial cell dysfunction.

DG Harrison - The Journal of clinical investigation, 1997 - Am Soc Clin Investig
… have been shown to lower eNOS expression. Exposure of cultured endothelial cells to TNF-
, hypoxia, and high concentrations of oxidized low density lipoprotein decrease eNOS levels …

Low-density lipoprotein-cholesterol-induced endothelial dysfunction and oxidative stress: the role of statins

N Hermida, JL Balligand - Antioxidants & redox signaling, 2014 - liebertpub.com
… Traditionally, endothelial dysfunction has been viewed as the result of … of low-density
lipoprotein-cholesterol (LDL-chol) is widely recognized as a causal factor of endothelial dysfunction

Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction

YR Kim, CS Kim, A Naqvi, A Kumar… - American Journal …, 2012 - journals.physiology.org
… -induced endothelial dysfunction and atheromatous plaque … cell dysfunction. Human LDL
stimulates human p66shc promoter activity and p66shc expression in human endothelial cells. …

Lowdensity lipoprotein size, high‐density lipoprotein concentration, and endothelial dysfunction in non‐insulin‐dependent diabetes

SF O'Brien, GF Watts, DA Playford, V Burke… - Diabetic …, 1997 - Wiley Online Library
… both endothelial and smooth muscle cell dysfunction in men with … endothelial dysfunction
was independently related to the degree … Endothelial dysfunction due to an abnormality in the …

Molecular determinants of oxidized low-density lipoprotein–induced leukocyte adhesion and microvascular dysfunction

L Liao, RM Starzyk, DN Granger - Arteriosclerosis, thrombosis, and …, 1997 - Am Heart Assoc
… leukocyte and endothelial cell adhesion molecules provide new insight concerning the
contribution of leukocyte adhesion to the endothelial barrier dysfunction elicited by oxLDL. The …

LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis

M Chen, T Masaki, T Sawamura - Pharmacology & therapeutics, 2002 - Elsevier
… As a new member of the NK cell gene … cell dysfunction. In addition, LOX-1 might also
have (patho)physiological effects on cell-cell interactions such as those exhibited by NK cell

[HTML][HTML] High density lipoprotein and it's dysfunction

E Eren, N Yilmaz, O Aydin - The open biochemistry journal, 2012 - ncbi.nlm.nih.gov
Plasma high-density lipoprotein cholesterol (HDL-C) levels do not predict functionality and
composition of high-density lipoprotein (HDL). Traditionally, keeping levels of low-density

Carbamylated low-density lipoprotein induces endothelial dysfunction

T Speer, FO Owala, EW Holy, S Zewinger… - European heart …, 2014 - academic.oup.com
… human aortic endothelial cells after treatment with carbamylated low-density lipoprotein (100 …
in human aortic endothelial cells treated with carbamylated low-density lipoprotein (100 µg/…