A comparative study of high-dose and low-dose ACTH therapy for West syndrome

S Yanagaki, H Oguni, K Hayashi, K Imai… - Brain and …, 1999 - Elsevier
low-dose ACTH treatment. As we had confirmed the effectiveness of low-dose ACTH therapy,
we designed the following prospective randomized controlled study of low-dose (0.005 mg/…

A low dose ACTH test to assess the function of the hypothalamic–pituitary–adrenal axis

S Rasmuson, T Olsson, E Hägg - Clinical endocrinology, 1996 - Wiley Online Library
… -term glucocorticoid therapy. DESIGN Insulin tolerance, low dose ACTH and standard ACTH
tests were … The ITT was performed less than 48 hours after the ACTH tests. Synacthen was …

Low-dose ACTH therapy for West syndrome: initial effects and long-term outcome

M Ito, H Aiba, K Hashimoto, S Kuroki, K Tomiwa… - Neurology, 2002 - AAN Enterprises
… In the current study, lower doses of synthetic ACTH were used compared with the classic
standard method, and the initial effects on seizures and long-term seizure outcome were almost …

The low dose (1 μg) ACTH stimulation test for assessment of the hypothalamo-pituitary-adrenal axis

A Beishuizen, JH Van Lijf, JFF Lekkerkerker… - The Netherlands Journal …, 2000 - Elsevier
ACTH to evaluate a physiologic response, which may result in false normal responses. The
proposed low dose (1 μg) ACTH … based medicine, the low dose ACTH test should replace the …

Comparison of two low dose ACTH therapies for West syndrome: their efficacy and side effect

Y Kondo, A Okumura, K Watanabe, T Negoro… - Brain and …, 2005 - Elsevier
… of adrenocorticotropic hormone (ACTH), the efficacy and side effects of two different regimens
of low dose ACTH therapy … patients with West syndrome (WS) were treated with ACTH. The …

Shortcomings in the low-dose (1 μg) ACTH test for the diagnosis of ACTH deficiency states

DHP Streeten - The Journal of Clinical Endocrinology & …, 1999 - academic.oup.com
… , continues to be a reliable indicator of the need for steroid therapy if the serum cortisol
response is subnormal; but unfortunately, it cannot be relied upon if the response is normal. It is …

Extremely low-dose ACTH therapy for West syndrome in Japan

M Ito - Brain and Development, 2001 - Elsevier
low-dose ACTH therapy for West syndrome To elucidate the long-term outcome of low-dose
ACTH therapy … who were treated with low-dose synthetic ACTH therapy between 1989 and …

High-dose, long-duration versus low-dose, short-duration corticotropin therapy for infantile spasms

RA Hrachovy, JD Frost Jr, DG Glaze - The Journal of pediatrics, 1994 - Elsevier
… Subsequently the patients in each group were randomly assigned to receive either low-dose
or high-dose ACTH therapy. Patients assigned to high-dose ACTH therapy were treated …

Extremely low-dose ACTH step-up protocol for West syndrome: maximum therapeutic effect with minimal side effects

H Oguni, S Yanagaki, K Hayashi, K Imai… - Brain and …, 2006 - Elsevier
… We studied the effectiveness of our new ACTH treatment strategy for West syndrome (WS),
which was based on the results of our previous extremely low-dose ACTH study. The subjects …

Comparison of adrenocorticotropin (ACTH) stimulation tests and insulin hypoglycemia in normal humans: low dose, standard high dose, and 8-hour ACTH-(1–24) …

EJ Nye, JE Grice, GI Hockings… - The Journal of …, 1999 - academic.oup.com
… that very much lower doses of exogenous ACTH were sufficient to cause ACTH and cortisol
… -(1–24) in patients with Addison’s disease and receiving long term glucocorticoid therapy. …